Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Epley vs. Semont-plus maneuver for posterior canal BPPV

Official title: Efficacy of the Epley Versus Semont-plus Maneuver in Patients With Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo: A Randomized Controlled Trial Using Quantitative Video-Nystagmography Measurement

Run by Military Hospital 175 · NCT07787559 · Data updated 2026-11-12

This trial tests whether the Epley maneuver or the Semont-plus maneuver more effectively treat posterior canal BPPV in adults.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment160 (estimated)
SponsorMilitary Hospital 175
Academic / other
Locations1 site (Ho Chi Minh City)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedOctober 30, 2027
Study endsNovember 30, 2027
Registry record updatedNovember 10, 2026
Trial IDNCT07787559 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older with unilateral, single-canal posterior canal BPPV (canalolithiasis) diagnosed by Barany criteria.

Probably not a fit

Patients with multi-canal involvement, unsafe cervical spine conditions, or inability to perform the maneuvers may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two established head-movement techniques used to treat posterior canal BPPV caused by canalolithiasis. Participants will receive either the Epley maneuver or the Semont-plus maneuver and will be assessed before treatment, 30 minutes after, and 3 days after to see which method better reduces involuntary eye movements and dizziness. Additional outcomes include time to dizziness resolution, rate of free-of-dizziness status, the effect of home repetition, and treatment-related side effects. Eligible participants are adults with unilateral, single-canal posterior canal BPPV diagnosed by Barany criteria. Exclusion criteria include multi-canal involvement, unsafe cervical conditions, inability to cooperate, or conditions preventing reliable videonystagmography.

Why it matters

Potential benefit: If successful, one maneuver may become the preferred treatment, potentially providing faster relief from dizziness.

How similar studies have gone: Previous work has demonstrated efficacy of positional maneuvers for BPPV, but direct head-to-head comparisons like this are less common.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older
* Posterior semicircular canal benign paroxysmal positional vertigo of the canalolithiasis type, diagnosed according to the Barany Society 2015 diagnostic criteria
* Unilateral involvement of a single semicircular canal

Exclusion Criteria:

* Involvement of more than one semicircular canal
* Any condition making the repositioning maneuver unsafe, including severe cervical spine disease with restricted range of motion or instability, previous cervical spine fracture, severe osteoporosis, unstable cardiovascular disease, or respiratory failure
* Unable to cooperate with the maneuver
* Any ocular or neurologic condition preventing technically adequate videonystagmography recording, such as inability to keep the eyes open, severe ptosis, or interfering spontaneous nystagmus from another cause

Where it's running

  • Military Hospital 175
    Ho Chi Minh City, Vietnam
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.