Vitamin C to shorten hospital stay for children with severe pneumonia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized Phase 4 trial enrolls 90 children aged 2–59 months admitted to a single pediatric hospital in Multan with WHO-defined severe pneumonia. After parental consent, participants are randomly assigned to receive standard antibiotic treatment with or without added vitamin C. Children with congenital heart disease, chronic respiratory illnesses, or immunosuppression are excluded. The primary outcome is length of hospital stay, with clinical recovery measured by resolution of danger signs and respiratory symptoms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* presenting with severe pneumonia
* ≤ 48-hours duration

Exclusion Criteria:

* Congenital heart disease
* Children with chronic respiratory illnesses i.e. Asthma, post tuberculosis bronchiectasis and cystic fibrosis
* Immunosuppressed i.e. primary immune deficiency, malignancy, on steroid therapy

Where it's running

• Children Hospital and Institute of Child Health
  Multan Khurd, Punjab Province, Pakistan Recruiting

Study contacts

• Study coordinator: Muhammad S Principal Investigator, MBBS
• Email: msulaman1432@gmail.com
• Phone: +92 302 2513701

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.