Vitamin B6 supplementation for preventing depression in pregnant women

The Correlation Between Vitamin B6 and Avoiding Depression in Pregnant and Peri-partum Women

Not applicable Interventional National Taiwan University Hospital · NCT06445933

This study is testing if taking Vitamin B6 during pregnancy can help prevent depression after childbirth in pregnant women.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages20 Years to 50 Years
SexFemale
SponsorNational Taiwan University Hospital Academic / other
Locations1 site (Taipei)
Trial IDNCT06445933 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effects of Vitamin B6 supplementation on preventing postpartum depression in pregnant women. A total of 120 participants will be randomly assigned to either receive Vitamin B6 or a placebo during their late pregnancy and for one month postpartum. The study employs a double-blind design to ensure unbiased results, with blood samples taken to measure Vitamin B6 levels at key points. The aim is to determine if Vitamin B6 can help maintain emotional stability and reduce the incidence of perinatal depression.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women aged 20-50 years, between 24-28 weeks of gestation, without a history of mental health conditions.

Not a fit: Patients who are allergic to Vitamin B6 will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a simple and effective preventive measure against postpartum depression for pregnant women.

How similar studies have performed: While the use of Vitamin B6 for mental health is promising, this specific approach in preventing postpartum depression is relatively novel and has not been extensively tested in similar studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant women at 24-28 weeks of gestation
* Without a personal history of depression, bipolar disorder, schizophrenia, or other mental health conditions.

Exclusion Criteria:

* Allergic to Vitamin B6

Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postpartum DepressionHeart Rate VariabilityVitaminsWearable devices
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.