Clinical trial Recruiting at 1 site Interventional Ages 8 and up

VisionApp test for ghosting in single-eye (monocular) vision

Official title: Assessment of the Accuracy and Repeatability of the VisionApp - Ghosting Measurement Protocol

Run by Indiana University · NCT07571538 · Data updated 2026-11-12

This test tries the VisionApp smartphone app to see if it can accurately measure ghosting in people with monocular diplopia.

Quick facts

Study typeInterventional
Ages8 Years and up
SexAll
Enrollment12 (estimated)
SponsorIndiana University
Academic / other
Locations1 site (Bloomington, Indiana)
StatusRecruiting
StartedOctober 10, 2025
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedAugust 24, 2026
Trial IDNCT07571538 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

People (adults and children) with plano to -5.00 D refractive error, ≤ -0.75 D astigmatism, recent eye exam, best-corrected visual acuity of 20/20 in each eye, no amblyopia or diagnosed ocular disease, and ability to follow the visit schedule are ideal candidates.

Probably not a fit

Patients with significant ocular disease, amblyopia, high refractive errors or astigmatism beyond the eligibility limits, systemic conditions or medications affecting vision, or those unable to attend an in-person visit are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will compare VisionApp measurements to standard clinical tests by having participants complete refraction, visual acuity checks, and lighting controls at the Clinical Optics Research Lab. Participants will wear a single-vision contact lens in one eye and two different multifocal lenses in the other eye while reporting perceived shadows or distortions using slider bars and numerical ratings. The protocol includes both adults and children with age-appropriate multifocal lenses and uses randomization to determine lens order. The study will analyze accuracy, repeatability, and reproducibility of the app-based ghosting measurements across sessions.

Why it matters

Potential benefit: If successful, this could provide a low-cost, easy way to measure and monitor ghosting that helps clinicians and patients choose and compare contact lens options.

How similar studies have gone: Some smartphone refraction tools have shown promising accuracy for measuring refractive error, but using an app specifically to quantify ghosting in monocular diplopia is relatively novel and less validated.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* has a refractive error between Plano and -5.00 D of sphere and cylinder components combined.
* has refractive cylinder (e.g., astigmatism) of -0.75 D or less
* has had a self-reported oculo-visual exam in the last 2 years
* has best-corrected visual acuity of at least 20/20 in each eye
* is not amblyopic or does not have any diagnosed ocular disease
* is willing and able to follow instructions and maintain the appointment schedule

Exclusion Criteria:

* has any systemic disease affecting ocular health and visual acuity
* is currently using any systemic or topical medications that could affect ocular health and visual acuity
* is participating in another eye related research study

Where it's running

  • Clinical Optics Research Lab
    Bloomington, Indiana, United States
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.