Virtual reality vision testing for patients with age-related macular degeneration

Virtual Reality (VR) Based Vision Test in Subjects With Age-related Macular Degeneration (AMD)

Not applicable Interventional Augenklinik Zurich West · NCT06241625

This study tests whether virtual reality can help people with age-related macular degeneration better understand their vision problems by comparing it to traditional eye tests.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages50 Years to 105 Years
SexAll
SponsorAugenklinik Zurich West Academic / other
Locations1 site (Zürich, Zurich)
Trial IDNCT06241625 on ClinicalTrials.gov

What this trial studies

This study evaluates the usability, tolerability, and repeatability of virtual reality (VR) tasks designed to assess contrast sensitivity in patients with age-related macular degeneration (AMD). Researchers aim to bridge the gap between existing functional measures and AMD lesions by using VR tools. The primary goal is to correlate the VR-based contrast sensitivity function metrics with conventional clinical measurements of retinal anatomy and visual function. Participants will undergo VR testing and quality optical coherence tomography imaging to gather comprehensive data.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older diagnosed with AMD who have a Snellen BCVA score of 20/100 or better.

Not a fit: Patients with significant oculomotor impairments, neurological conditions, or those unwilling to use a VR headset may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a more effective and engaging method for assessing vision in patients with AMD.

How similar studies have performed: While the use of VR in clinical assessments is emerging, this specific application in AMD is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Subjects ≥18 years of age diagnosed with AMD
2. Subject Snellen BCVA score is 20/100 or better
3. Ability to undergo quality optical coherence tomography (OCT) imaging
4. Willing and able to give written informed consent

Exclusion Criteria:

1. Unwilling to use headset
2. Previous negative experience with a VR headset (eg, motion sickness, discomfort)
3. Any known oculomotor impairment that would impact the ability of the subject to perform the tasks (eg, nystagmus, proptosis, apraxia of eyelid opening)
4. Any manifest neurological or cognitive condition that would impair the subject's understanding or performance on the test (eg, Alzheimer's disease, Parkinson's disease)
5. Any physical limitations that would prohibit the use of the VR headset (eg, neck problems)

Where this trial is running

Zürich, Zurich

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Age-Related Macular Degeneration
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.