Virtual reality relaxation to reduce pain during elective egg retrieval

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled trial enrolls women aged 18–45 undergoing elective oocyte cryopreservation and randomly assigns them to routine care alone or routine care plus a roughly 20-minute VR-based relaxation session before retrieval. Pain is measured using validated scales including the visual analog scale before and after the procedure, with secondary outcomes of pain sensitivity, analgesic consumption, and physiological parameters. Participants with contraindications to VR (for example, history of seizures, severe motion sensitivity, migraines, or current use of certain psychoactive medications) are excluded. The VR intervention is delivered via a headset in the clinic waiting area immediately prior to the oocyte retrieval.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women undergoing elective oocyte retrieval for fertility preservation.
* Age 18-45 years.
* Ability to provide informed consent.

Exclusion Criteria:

* Use of pain relief, anti-anxiety, or antidepressant medications prior to the intervention.
* Any condition for which VR use is not recommended, including:

  * History of seizures
  * Sensitivity to flashing light or motion
  * Migraine headaches
  * Predisposition to nausea or dizziness (e.g., vertigo)
* Any injury to the eyes, face, or neck limiting use of the VR device, including blindness.

Where it's running

• Hadassah Medical Organization
  Jerusalem, Israel Recruiting

Study contacts

• Principal investigator: Anat Hershko-Klement, MD — Hadassah Medical Center, Mount Scopus Campus, Jerusalem, Israel
• Study coordinator: Adar Hamrani, MD
• Email: adarha@hadassah.org.il
• Phone: +972-54-5560848

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.