Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Video-based proprioceptive home exercise for trunk and limb control in ALS

Official title: Examining the Effectiveness of Video-Based Proprioceptive Home Exercise Program in Amyotrophic Lateral Sclerosis Patients

Run by Tarsus University · NCT07292545 · Data updated 2026-11-12

This program will try a video-based proprioceptive home exercise routine for adults with ALS who can sit independently to see if it improves trunk and limb control and daily activities.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment20 (estimated)
SponsorTarsus University
Academic / other
Locations1 site (Mersin, TARSUS)
StatusRecruiting
StartedJuly 14, 2025
Main results expectedOctober 1, 2026
Study endsDecember 1, 2026
Registry record updatedDecember 18, 2025
Trial IDNCT07292545 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–70 with a definite ALS diagnosis by Gold Coast criteria who can sit independently and have no cognitive problems are eligible.

Probably not a fit

Patients who cannot sit independently, cannot complete active joint movements, or have other neurological, orthopedic, or visual conditions mimicking ALS are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-site interventional project enrolls 20 adults with a definite ALS diagnosis to characterize proprioceptive function and deliver a home-based video proprioceptive exercise program. Baseline testing includes a detailed neurological and proprioceptive sensory examination and the Revised ALS Functional Rating Scale (R-ALSFRS). Participants follow the video program three days per week for eight weeks, with repeat neurological and proprioceptive assessments and R-ALSFRS scoring at the end of the intervention. The study focuses on changes in trunk and limb control and daily life activity measures following the intervention.

Why it matters

Potential benefit: If successful, the program could improve trunk and limb control and increase independence in daily activities for people with ALS.

How similar studies have gone: This approach is novel for ALS—sensory and proprioceptive involvement has been suggested in research, but there are no prior clinical trials of proprioceptive training in ALS patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:Inclusion Criteria:

* ALS patients aged 18-70
* Those with a definite ALS diagnosis according to the Gold Coast criteria
* Those who can sit independently
* Those who have no cognitive problems
* Those who agree to participate in the study will be included in the study.

Exclusion Criteria:

* ALS patients with neurological, orthopedic or visual dysfunction mimicking ALS,
* Those who cannot complete active joint movements in the upper and lower extremities,
* ALS patients who do not agree to participate in the study will not be included in the study.

Where it's running

  • Tarsus University
    Mersin, Tarsus, Turkey (Türkiye)
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.