VEVYE (cyclosporine 0.1%) for short-term symptom and sign improvement in dry eye at a neuro-ophthalmology clinic

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a 6-month prospective observational follow-up of adults seen in a neuro-ophthalmology clinic who are prescribed VEVYE as part of routine care for clinically diagnosed dry eye (OSDI ≥23 and at least one objective sign). Patients receive topical cyclosporine 0.1% per their treating clinician and complete standardized symptom questionnaires and clinic assessments at baseline and scheduled follow-ups. The non-randomized design captures real-world treatment patterns and includes a subgroup with neurotrophic keratitis. Outcomes focus on short-term changes in patient-reported symptoms and objective ocular surface signs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age18 yr or older Diagnosis of neuro-ophthalmic condition Clinical diagnosis of dry eye disease OSDI score of 23 or greater at baseline Objective sign present Indicated for VEVYE prior to enrollment Ability and willingness to complete study visits and questionnaires

Exclusion Criteria:

* Patients with a corneal ulcer Use of another cyclosporine or lifitegrast product within 30 days of baseline Ocular surgery within 30 prior to baseline Active ocular infection or severe ocular surface condition unrelated to DED Contact lens wearers ( must be off contacts for 30 days and the duration of trial) Any condition that prevents compliance or informed consent Subjects with severe scarring / zero sensitivity

Where it's running

• Neuro Ophthalmology of TX
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Rosa A. Tang — Neuro Ophthalmology of TX
• Study coordinator: Laura Perez
• Email: lperez@neuroeye.com
• Phone: 12817238593

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Lacrifill to Help Prevent Post-Curgery Dry Eye After Cataract Surgery

  This study tests Lacrifill to see if it helps prevent dry eye symptoms after unilateral cataract surgery.

  Recruiting at 2 sites Phase 4 Eye Research Associates, LLC · Pittsburg, Kansas and 1 other locations · NCT07796178

• Tear-Fluid Stability Testing with iTrace, BOSA, OPD-Scan III, and IDRA for Dry Eye

  A Phase 4 study tests whether four eye devices can detect tear film stability in adults with normal tear film.

  Recruiting Phase 4 Vance Thompson Vision · Sioux Falls, South Dakota · NCT07790211

• OT202 1% eye drops for moderate to severe dry eye

  This phase 3 study tests whether 1% OT202 eye drops help people with moderate to severe dry eye better than a placebo.

  Recruiting Phase 3 Ocumension Therapeutics (Suzhou) Co., Ltd · Bengbu, Anhui and 48 other locations · NCT07740564

• Tyrvaya Nasal Spray for Comfort in Contact Lens Wearers

  This study tests whether using Tyrvaya twice daily can improve comfort for adults who wear soft contact lenses and have dry eye symptoms.

  Recruiting Ocular Aesthetics, LLC dba Ocular Clinical Trials · Houston, Texas · NCT07705893

• Long-term effects of Acoltremon vs. control in dry eye disease

  This study tests whether Acoltremon eye drops help people with dry eye over a year compared with a preservative-free artificial tear, at a single center.

  Recruiting The Eye Care Institute · Louisville, Kentucky · NCT07659626

• Effect of Dry Eye Treatment on Corneal Astigmatism Measurements

  This study tests whether short-term treatment for dry eye changes how consistently three devices measure corneal astigmatism in people preparing for cataract surgery.

  Recruiting Eye & ENT Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT07657858

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.