Clinical trial Recruiting at 1 site Interventional Ages 18 to 35

Vestibulo-ocular reflex exercises added to postural training for amateur athletes with chronic ankle instability

Official title: The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training on Visuo-Motor Reaction Performance, Fear Avoidance Behaviors Related to Sports Injuries and Kinesiophobia in Amateur Athletes With Chronic Ankle Instability

Run by Bahçeşehir University · NCT07760233 · Data updated 2026-11-12

This test checks whether adding vestibulo-ocular reflex (VOR) exercises to standard postural stabilization helps amateur athletes with chronic ankle instability.

More Ankle Sprain trials

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexAll
Enrollment32 (estimated)
SponsorBahçeşehir University
Academic / other
Locations1 site (Istanbul, Turkey)
StatusRecruiting
StartedJuly 25, 2026
Main results expectedJuly 25, 2027
Study endsJuly 25, 2027
Registry record updatedOctober 28, 2026
Trial IDNCT07760233 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Amateur athletes aged 18–35 with unilateral chronic ankle instability and documented CAI metrics (CAIT-T ≤ 24, FAAM < 90%, FAAM-S < 80%, and side-to-side dorsiflexion difference ≥ 2.5 cm).

Probably not a fit

Individuals without chronic ankle instability, different age range, or those without the specified functional impairment may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Chronic ankle instability (CAI) persists after lateral ankle sprains and involves motor, sensory, and psychological factors affecting function. The trial investigates whether incorporating vestibulo-ocular reflex exercises into postural stabilization improves dynamic balance and sport-specific sensorimotor control in amateur athletes. Participants complete a postural stabilization program, with or without added VOR training, to see if the combined approach enhances gaze stability and visuomotor performance during dynamic tasks. Outcomes focus on sensorimotor control, functional measures, and relevant clinical scales in CAI. The study adopts an interventional design in a real-world athletic setting to inform rehabilitation strategies for CAI.

Why it matters

Potential benefit: If successful, the combined VOR and postural training could improve balance, gaze stability, and sports readiness for athletes with CAI.

How similar studies have gone: Prior work shows benefit from integrated sensorimotor and gaze control rehabilitation in CAI, though adding targeted VOR exercises is a novel aspect in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being between 18 and 35 years of age.
* Being classified as a Tier 2 athlete according to the McKay et al. Participant Classification Framework (trained/developmental level).
* Having a history of at least one lateral ankle sprain (LAS) occurring at least 12 months before enrollment, resulting in swelling, pain, and functional impairment, and followed by persistent instability.
* Having the most recent ankle sprain at least 3 months before study enrollment.
* Having a history of recurrent ankle sprains or episodes of "giving way."
* Having a diagnosis of unilateral chronic ankle instability (CAI).
* Having a Cumberland Ankle Instability Tool - Turkish Version (CAIT-T) score of ≤24.
* Having a Foot and Ankle Ability Measure (FAAM) score of \<90%.
* Having a Foot and Ankle Ability Measure Sports subscale (FAAM-S) score of \<80%.
* A side-to-side difference of ≥2.5 cm in Weight-Bearing Lunge Test distance, with the affected side demonstrating less dorsiflexion than the unaffected side.

Exclusion Criteria:

* History of acute lateral ankle sprain within the last 3 months.
* History of lower extremity surgery.
* History of acute injury to other musculoskeletal structures of the lower extremity joints within the last 3 months that affected joint integrity and function and caused interruption of desired physical activity for at least one day.
* History of balance or vestibular disorders, including cerebellar, vestibular, cochlear, or inner ear dysfunction.
* Visual problems that may affect the administration or interpretation of the Dynamic Visual Acuity Test, including a history of amblyopia, diplopia, or significant visual loss.
* Persistent symptoms related to a previous concussion or traumatic brain injury.

Where it's running

  • Reset Fizyoterapi
    Istanbul, Turkey, Turkey (Türkiye)
    Recruiting

Study contacts

  • Principal investigator: Mustafa Fatih Çetintaş, PT, PhD (c) — Bahçeşehir University
  • Study coordinator: Mustafa Fatih Çetintaş, PT, PhD (c)
  • Email: mfcetintas@gmail.com
  • Phone: +905336654580

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.