NMES combined with PNF for ankle sprain rehab
Official title: Effects of Neuromuscular Electrical Stimulation Combined With Proprioceptive Neuromuscular Facilitation in Adults With a History of Ankle Sprain
Run by Fooyin University · NCT07190599 · Data updated 2026-11-12
This program will test whether adding electrical muscle stimulation (NMES) to PNF stretching helps 18–30-year-olds with past ankle sprains reduce pain and improve balance, strength, and movement.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Fooyin University Academic / other |
| Locations | 1 site (Kaohsiung City, No. 151, Jinxue Road, Daliao District) |
| Status | Recruiting |
| Started | October 1, 2025 |
| Main results expected | March 31, 2026 |
| Study ends | July 31, 2026 |
| Registry record updated | November 17, 2025 |
| Trial ID | NCT07190599 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–30 with a prior ankle sprain who do not have fractures, dislocations, grade III sprains, significant swelling, bony restrictions, neuropathy, or other neuromuscular disorders.
✕Probably not a fit
Patients with recent fractures, dislocations, grade III sprains, active swelling, bony mechanical restrictions, neuropathy, or other neuromuscular conditions are unlikely to be eligible or benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional trial will enroll 60 adults aged 18–30 with a history of ankle sprain and randomize them into two groups of 30. The experimental group will receive PNF stretching combined with neuromuscular electrical stimulation (NMES) while the control group will receive PNF stretching alone, with both groups training three times per week for four weeks (12 sessions total). Outcomes measured before and after the program include pain, balance, range of motion, proprioception, strength, joint mobility, and functional limitations. Participants with fractures, dislocations, grade III sprains, bony restrictions, swelling, neuropathy, or other neuromuscular disorders are excluded.
Why it matters
Potential benefit: If successful, combining NMES with PNF could reduce pain and improve balance, strength, and functional ability more than PNF alone for young adults with chronic ankle problems.
How similar studies have gone: Separate studies support NMES for strengthening and PNF for flexibility and proprioception, but direct evidence for the combined NMES+PNF approach in ankle sprain rehab is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-30 years * Adults with a history of ankle sprain Exclusion Criteria: * Participants with ankle fractures, dislocations, grade III ankle sprains, bony restrictions, swelling, neuropathy, or any other neuromuscular disorders are excluded.
Where it's running
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Fooyin University
Kaohsiung City, No. 151, Jinxue Road, Daliao District, Taiwan Recruiting
Study contacts
- Study coordinator: I-Hsuan Chen
- Email: Y0894@fy.edu.tw
- Phone: 886-7-7811151 #7043
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.