VentilO versus clinician ventilator settings after cardiac surgery
Frequency of Respiratory Acidosis in the Intensive Care Unit After Postoperative Cardiac Surgery. Impact of Using VentilO Application
NA · Laval University · NCT06826794
This will see if using the VentilO app to set ventilator rate and breath size right after ICU admission reduces episodes of respiratory acidosis in intubated adults after heart surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 76 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Laval University (other) |
| Locations | 1 site (Québec, Quebec) |
| Trial ID | NCT06826794 on ClinicalTrials.gov |
What this trial studies
This is a randomized, open-label comparison of initial ventilator settings chosen by clinicians versus settings recommended by the VentilO application for adults intubated immediately after cardiac surgery. Patients are ventilated in controlled modes (Assist Control or SIMV) and the study compares respiratory rate, tidal volume, and resulting minute ventilation between the two approaches. The primary outcome is the frequency of respiratory acidosis during early ICU care. The trial is conducted at a single tertiary cardiac ICU in Québec.
Who should consider this trial
Good fit: Adults over 18 who are intubated and admitted to the ICU immediately after any cardiac surgery, receiving controlled-mode ventilation (Assist Control or SIMV) with height and weight documented are ideal candidates.
Not a fit: Patients who are mainly breathing spontaneously on arrival, are extubated on arrival, or lack documented height/weight are excluded and unlikely to benefit from the intervention.
Why it matters
Potential benefit: If successful, VentilO-guided settings could reduce episodes of respiratory acidosis and improve early ventilator management for post-cardiac surgery patients.
How similar studies have performed: Other decision-support tools for ventilator settings have shown mixed improvements in parameter consistency and gas control, but VentilO-specific evidence is limited and the application is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (\> 18 years old) * Intubated patients admitted to intensive care immediately post-operatively after cardiac surgery (all cardiac surgery combined) * Ventilation in controlled mode (Assist Control or SIMV) Exclusion Criteria: * Absence of anthropometric data (height and weight) of patients available in the patient file * Respiratory cycles mainly spontaneous on arrival * Patient extubated on arrival in intensive care
Where this trial is running
Québec, Quebec
- Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval — Québec, Quebec, Canada (RECRUITING)
Study contacts
- Study coordinator: Francois Lellouche Principal investigator, MD, PhD
- Email: francois.lellouche@criucpq.ulaval.ca
- Phone: 1-418-656-8711
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Mechanical Ventilation Complication, Respiratory Acidosis