Venous congestion and kidney risk after open-heart surgery: a look at VExUS scores
Official title: Evaluation of the Association Between the VEXUS Score and Hemodynamic Status and the Occurrence of Acute Kidney Injury After Open-Heart Surgery
Run by Hanoi Medical University · NCT07805564 · Data updated 2026-11-12
This study tests whether the VExUS ultrasound score can predict acute kidney injury and other outcomes after open-heart surgery in adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 135 (estimated) |
| Sponsor | Hanoi Medical University Academic / other |
| Locations | 1 site (Hanoi, Hanoi) |
| Status | Recruiting |
| Started | January 7, 2026 |
| Main results expected | September 30, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT07805564 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older undergoing elective or emergent open-heart surgery with cardiopulmonary bypass.
✕Probably not a fit
Patients with severe preoperative kidney disease, liver disease, or those not undergoing PiCCO monitoring may have limited applicability of findings to their care.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study enrolls adults undergoing cardiac surgery with cardiopulmonary bypass and tracks postoperative VExUS scores to see if venous congestion relates to AKI and complications. A predefined subgroup with PiCCO monitoring will be analyzed to explore connections between VExUS findings and PiCCO hemodynamic parameters. The aim is to improve understanding of how venous congestion influences outcomes after surgery and whether VExUS could serve as a prognostic tool. All participants will be analyzed for the development of AKI and other postoperative events relevant to recovery. No interventional therapy is mandated by the protocol.
Why it matters
Potential benefit: If successful, VExUS could help clinicians identify patients at higher risk of AKI and guide fluid management after surgery.
How similar studies have gone: Previous work has suggested associations between venous congestion and adverse renal outcomes, but evidence linking VExUS with detailed hemodynamics in cardiac surgery is limited and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients aged 18 years or older * Undergoing elective or emergent open-heart surgery with the use of Cardiopulmonary Bypass (CPB) Exclusion Criteria: * Severe tricuspid regurgitation End-stage chronic kidney disease (estimated glomerular filtration rate below 15 mL per minute per 1.73 square meters) * Preoperative use of an intra-aortic balloon pump (IABP) * Preoperative use of extracorporeal membrane oxygenation (ECMO) or a ventricular assist device (VAD) * Liver cirrhosis, portal hypertension, or portal vein thrombosis * Refusal to participate by the patient or the patient's legally authorized representative
Where it's running
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Hanoi Medical University Hospital
Hanoi, Hanoi, Vietnam Recruiting
Study contacts
- Study coordinator: Tu Nguyen Huu, Prof
- Email: nguyenhuutu@hmu.edu.vn
- Phone: +84904176397
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.