Vending machines providing naloxone to prevent opioid overdoses

Vending Machine Naloxone Distribution for Your Community (VENDY): Increasing Reach and Implementation of Naloxone Distribution

Phase 4 Interventional University of Colorado, Denver · NCT06429436

This study tests whether placing vending machines that offer free naloxone in communities can help more people access this lifesaving medication to prevent opioid overdoses.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment4000 (estimated)
SexAll
SponsorUniversity of Colorado, Denver Academic / other
Locations3 sites (Denver, Colorado and 2 other locations)
Trial IDNCT06429436 on ClinicalTrials.gov

What this trial studies

This pilot program evaluates the Vending machine Naloxone Distribution for Your community (VENDY) initiative, which aims to enhance access to naloxone through community-placed vending machines. The program will be implemented in three communities, where naloxone will be distributed for free to individuals who wish to obtain it. The study will assess the reach of naloxone distribution, the adoption rate among sites and staff, and the fidelity to restocking and maintenance protocols for the machines.

Who should consider this trial

Good fit: Any community member who wishes to obtain naloxone is eligible to use the vending machines.

Not a fit: Individuals who are unable to enter a code on the vending machine or open a kiosk will not benefit from this program.

Why it matters

Potential benefit: If successful, this initiative could significantly increase access to naloxone, thereby reducing opioid overdose deaths in the community.

How similar studies have performed: Other studies have shown that innovative distribution methods like vending machines can effectively increase access to naloxone, suggesting a promising approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Any person in the community who desires to obtain naloxone will be able to use the machines

Exclusion Criteria:

* Inability to enter a code on a vending machine or open a kiosk.

Where this trial is running

Denver, Colorado and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Harm ReductionNaloxoneOpioid Overdose
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.