Vector® ultrasonic system versus mini-five curettes for non-surgical treatment of periodontitis
Official title: A Randomized Single-Blind Clinical Trial Comparing the Clinical and Radiographic Outcomes of the Vector® Ultrasonic System and Minimally Invasive Hand Instrumentation (Mini-Five Curettes) in Non-Surgical Periodontal Therapy
Run by Hacettepe University · NCT07452640 · Data updated 2026-11-12
This trial will test whether the Vector® ultrasonic system or manual mini-five curettes better reduce pocket depth and improve attachment in adults with Stage III–IV periodontitis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Hacettepe University Academic / other |
| Locations | 1 site (Ankara) |
| Status | Recruiting |
| Started | February 19, 2026 |
| Main results expected | February 2027 |
| Study ends | February 2028 |
| Registry record updated | March 5, 2026 |
| Trial ID | NCT07452640 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–65 years old with Stage III or IV periodontitis, single-rooted teeth in both jaws with vertical intrabony defects (≥2 mm) and probing depths ≥5 mm, who are systemically healthy (ASA I–II) and can attend follow-ups are ideal candidates.
✕Probably not a fit
Patients with furcation involvement, heavy smokers (>10 cigarettes/day), pregnant people, teeth with advanced mobility or horizontal bone loss, recent periodontal treatment, or those unwilling to follow-up are unlikely to benefit or are excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, controlled, single-blind trial at Hacettepe University compares two mechanical debridement methods for non-surgical periodontal therapy: the Vector® ultrasonic system and manual mini-five curettes. Participants with Stage III or IV periodontitis and vertical intrabony defects will be randomly assigned to one of the two treatment arms. Clinical measures (probing depth, clinical attachment level, bleeding on probing, plaque index) will be recorded at baseline and 1, 3, 6, and 12 months, with standardized radiographs at baseline, 6, and 12 months. The primary outcome is change in clinical attachment level at 12 months, with probing depth reduction and radiographic bone level change as secondary outcomes.
Why it matters
Potential benefit: If successful, the Vector® system could provide less-traumatic, equally or more effective non-surgical cleaning that better preserves root and periodontal tissues.
How similar studies have gone: Prior research generally shows that ultrasonic and manual debridement produce comparable clinical improvements, while the Vector® system is a more novel, less extensively studied ultrasonic approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adults aged 18-65 years Willing to participate and provided written informed consent Presence of single-rooted teeth in both maxilla and mandible with vertical bone defects (radiographic intrabony defect ≥2 mm and probing depth ≥5 mm) Diagnosis of Stage III or Stage IV periodontitis Systemically healthy or Systemically healthy patients or American Society of Anesthesiologists (ASA) physical status I-II. Exclusion Criteria: Periodontal treatment within the last 6 months Teeth with furcation involvement Smoking more than 10 cigarettes per day Pregnancy Age under 18 years Patients unwilling to attend regular follow-up visits Previously endodontically treated tooth at the treatment site Poor compliance with oral hygiene instructions Single-rooted teeth with horizontal bone loss extending close to the apical third Teeth with mobility grade II or III Previous flap surgery or regenerative periodontal treatment at the study site
Where it's running
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Hacettepe University Facultyof Dentistry
Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Abdullah Cevdet Akman — Hacettepe University
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.