Using whole blood for prehospital emergency care in hemorrhage cases
Finnish Prehospital Whole Blood Study
NA · Finnish Red Cross Blood Service · NCT05744583
This study tests if a new type of whole blood can help patients with severe bleeding in emergency situations better than the usual blood transfusions.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Finnish Red Cross Blood Service (other) |
| Locations | 1 site (Lahti) |
| Trial ID | NCT05744583 on ClinicalTrials.gov |
What this trial studies
This study evaluates the use of a new whole blood product, LTOWB, in prehospital emergency medical services in Finland for patients experiencing hemorrhage. The research aims to determine the feasibility and effectiveness of administering this cold-stored, leucoreduced whole blood product compared to traditional packed red blood cell transfusions. The study will involve three emergency medical service areas that currently utilize prehospital blood products, with other services providing control data. The goal is to assess how early blood transfusion impacts patient outcomes in cases of severe bleeding.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients who require a blood transfusion during prehospital emergency care.
Not a fit: Patients under 18 years old will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this approach could significantly reduce mortality rates in patients suffering from hemorrhagic shock by enabling faster and more effective blood transfusions.
How similar studies have performed: Other studies have shown promising results with the use of whole blood in emergency settings, indicating that this approach is gaining traction internationally.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: -All adult patients that have been given a blood transfusion during prehospital emergency care Exclusion Criteria: \- Age less than 18 years
Where this trial is running
Lahti
- PH00 — Lahti, Finland (RECRUITING)
Study contacts
- Principal investigator: Jouni Lauronen, MD, PhD — Finnish Red Cross Blood Service
- Study coordinator: Jouni Lauronen, MD, PhD
- Email: jouni.lauronen@veripalvelu.fi
- Phone: +358 50 3741177
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hemorrhage, Transfusion, Prehospital emergency care