Using virtual reality to improve cognitive function in breast cancer survivors

Virtual Reality-Based Cognitive Intervention for Women With Cognitive Complaints Following Breast Cancer Treatment

NA · Chungnam National University · NCT05653596

This study is testing if using virtual reality with nature scenes can help improve thinking skills in women who have had chemotherapy for breast cancer.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages19 Years to 64 Years
SexFemale
SponsorChungnam National University (other)
Drugs / interventionschemotherapy
Locations1 site (Daejeon)
Trial IDNCT05653596 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of a nature-based cognitive intervention delivered through virtual reality (VR) to restore cognitive function in women who have undergone chemotherapy for breast cancer. Participants will be screened for cognitive issues and then randomly assigned to either an experimental group receiving the VR intervention or a control group. The VR intervention consists of immersive video scenes featuring natural environments designed to stimulate cognitive engagement. The study seeks to address the cognitive dysfunction commonly experienced by breast cancer survivors.

Who should consider this trial

Good fit: Ideal candidates are women currently undergoing chemotherapy for breast cancer who report cognitive difficulties.

Not a fit: Patients with metastatic breast cancer or those with neurological disorders may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly improve cognitive function and quality of life for women recovering from breast cancer.

How similar studies have performed: Previous studies have shown promise in using VR for cognitive rehabilitation, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being treated with chemotherapy for breast cancer
* Having affirmative responses to three questions about cognitive problems and their impact on daily performance
* Having FACT-Cog scores of 58 or less
* Having Mini-Cog scores of 3 and higher
* Having the ability to read, understand or respond to questionnaires and cognitive assessment
* Being willing to participate and able to provide written informed consent

Exclusion Criteria:

* Having metastatic breast cancer
* Having Patient Health Questionnaire-2 score of 3 and higher
* Being diagnosed with neurological disorders such as dementia, multiple sclerosis, or traumatic brain injury
* Having epilepsy or seizure
* Having 'quite a bit' or 'extremely' severe level of nausea and vomiting
* Having visual or hearing impairments
* Having other problems that prevent them from wearing the VR headset

Where this trial is running

Daejeon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Breast Cancer, Cognitive Dysfunction, Virtual Reality

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.