Using virtual reality to help manage pain in children with sickle cell disease

Changing the View of Pain: Using Virtual Reality As Adjunctive Therapy for Sickle Cell Pain in Pediatric Patients

Not applicable Interventional Louisiana State University Health Sciences Center in New Orleans · NCT06773715

This study tests if using virtual reality can help children with sickle cell disease feel less pain during their hospital stays compared to just standard pain management.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages8 Years to 21 Years
SexAll
SponsorLouisiana State University Health Sciences Center in New Orleans Academic / other
Locations1 site (New Orleans, Louisiana)
Trial IDNCT06773715 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of virtual reality as an adjunct therapy for managing vaso-occlusive pain in children with sickle cell disease. Participants will be randomly assigned to receive either standard pain management or standard management plus daily virtual reality experiences during their hospital stay. The study will assess pain severity and opioid consumption through surveys completed by the patients. By exploring this innovative approach, the researchers hope to enhance pain relief and patient satisfaction during painful episodes.

Who should consider this trial

Good fit: Ideal candidates are children aged 8 to 21 years who are admitted for vaso-occlusive pain crises related to sickle cell disease.

Not a fit: Patients with severe complications from sickle cell disease or those unable to use virtual reality equipment may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce pain and opioid use in children experiencing vaso-occlusive crises.

How similar studies have performed: While the use of virtual reality in medical settings has been explored, this specific application for sickle cell pain management is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patient ≥ 8 up to 21 years of age
2. Presenting to CHNOLA ER or outside facility with chief complaint of vaso-occlusive pain crisis, requiring inpatient admission for further pain management
3. No known cognitive or neurological deficits
4. Parental/guardian permission (informed consent) and if appropriate, child assent.

Exclusion Criteria:

1. Patients aged 7-years-old and younger.
2. Patents upon admission found to have sequela of their sickle cell disease that would require medical therapy greater than the standard of care for a vaso-occlusive pain event. This includes acute chest syndrome, splenic sequestration, post-operative pain, and/or cerebrovascular accident
3. Patients who are developmentally or cognitively incapable of using VR equipment and answering questions appropriately
4. Failure to obtain or refusal to provide parental/guardian permission (informed consent) and if appropriate child assent
5. Patient has previously participated in the study
6. Study team is unable to initiate study interventions within the first 24 hours of a patient's admission

Where this trial is running

New Orleans, Louisiana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sickle Cell DiseaseVaso-occlusive Pain Episodesvirtual realityadjunctive therapyopiate consumptionpain reduction
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.