Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 and up

Using virtual reality to help healthcare workers with PTSD

Official title: Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers

Run by Weill Medical College of Cornell University · NCT04887116 · Data updated 2026-11-12

This study is testing a virtual reality program to see if it can help healthcare workers and COVID-19 patients with PTSD feel better after experiencing trauma on the job.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment20 (estimated)
SponsorWeill Medical College of Cornell University
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedOctober 5, 2023
Main results expectedJanuary 2027
Study endsJanuary 2027
Registry record updatedSeptember 16, 2026
Trial IDNCT04887116 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include English-speaking healthcare workers or COVID-19 patients aged 18 and older who have been diagnosed with PTSD or sub-threshold PTSD and are medically stable.

Probably not a fit

Patients with significant unstable medical illnesses, current suicidal or homicidal risks, or those with a history of psychotic disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop and test a virtual reality environment designed to treat posttraumatic stress disorder (PTSD) in healthcare workers and COVID-19 patients who have experienced occupational-related trauma. The approach utilizes virtual reality exposure therapy, which has a history of effectiveness in treating PTSD by allowing patients to confront and process their traumatic experiences in a controlled setting. Participants will be assessed for PTSD symptoms and other psychological issues through structured clinical interviews and self-report measures. The goal is to provide a novel therapeutic option for those affected by the psychological impact of the COVID-19 pandemic.

Why it matters

Potential benefit: If successful, this approach could significantly improve the mental health and quality of life for healthcare workers and COVID-19 patients suffering from PTSD.

How similar studies have gone: Previous studies have shown success in using virtual reality for PTSD treatment in military veterans and first responders, indicating potential for this approach in healthcare workers.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* A COVID-19 patient or any healthcare worker providing medical care or support who experiences occupational-related trauma
* English-speaking
* Age ≥18
* Medically stable
* Diagnosed with PTSD or sub threshold PTSD
* Ability to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments
* Stable on psychotropic medication for the prior 60 days

Exclusion Criteria:

* Current significant unstable medical illness such that the participant could not attend sessions regularly or complete assessments
* Patients who in the investigator's judgment pose a current homicidal, suicidal or other risk
* Lifetime or Current diagnosis of schizophrenia or other psychotic disorder
* Participation in a clinical trial or concurrent evidence-based treatment for psychiatric conditions or PTSD during the previous 3 months
* History of motion sickness or seizures

Where it's running

  • Weill Cornell Medicine
    New York, New York, United States
    Recruiting

Study contacts

  • Principal investigator: JoAnn Difede, PhD — Weill Medical College of Cornell University
  • Study coordinator: Isabelle McLeod Daphnis, BS
  • Email: sum4009@med.cornell.edu
  • Phone: 3108256016

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.