Using vagal nerve stimulation to reduce chronic migraine pain
Effects of Vagal Nerve Stimulation on Pain Frequency and Intensity in Chronic Migraine
This study is testing if a new noninvasive treatment using vagus nerve stimulation can help people with chronic migraines feel better when other treatments haven't worked.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 128 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Rawalpindi, Punjab) |
| Trial ID | NCT06191016 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of noninvasive vagus nerve stimulation (nVNS) in reducing the frequency and intensity of chronic migraine attacks. Researchers aim to assess the feasibility, safety, and acceptance of this neuromodulation technique as a potential treatment option for individuals suffering from chronic migraines. The study will compare the effects of active vagal nerve stimulation against a sham treatment to determine its efficacy in alleviating migraine symptoms. By focusing on patients who have not responded to traditional migraine treatments, this research seeks to provide a new avenue for managing chronic migraine.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with chronic migraines, experiencing headaches for 15 or more days per month for over three months.
Not a fit: Patients with mental illness, photophobia, or those with cranial implants or shunts may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could offer a new, effective treatment option for individuals suffering from chronic migraines, improving their quality of life.
How similar studies have performed: While vagus nerve stimulation has shown promise in other studies for various conditions, this specific application for chronic migraine is still being explored and may be considered novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chronic migraine (headache for 15 or more days/month for more than three months), Migraine with/without aura Exclusion Criteria: * Mental illness, Photophobic individual, Presence of shunt and/or implant at the cranial region
Where this trial is running
Rawalpindi, Punjab
- Pakistan Railway General Hospital — Rawalpindi, Punjab, Pakistan (Recruiting)
Study contacts
- Principal investigator: Mirza Obaid Baig, MSPT — Riphah International University
- Study coordinator: Rabia Nasir, DPT
- Email: Rabianasir123@gmail.com
- Phone: 0092 331 9303051
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.