Using ultrasound to predict outcomes in emergency patients with pulmonary embolism
Official title: Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism
Run by WellSpan Health · NCT05050617 · Data updated 2026-11-12
This study is testing whether using ultrasound in the emergency room can help doctors predict how well patients with pulmonary embolism will do in the short term.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | WellSpan Health Academic / other |
| Locations | 1 site (York, Pennsylvania) |
| Status | Recruiting |
| Started | September 9, 2021 |
| Main results expected | September 2026 |
| Study ends | December 2026 |
| Registry record updated | June 3, 2026 |
| Trial ID | NCT05050617 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been diagnosed with acute pulmonary embolism confirmed by CT imaging.
✕Probably not a fit
Patients under 18 years of age, those unable to provide informed consent, or individuals with a prior diagnosis of pulmonary embolism may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines how point-of-care echocardiography can predict short-term adverse outcomes in emergency department patients diagnosed with acute pulmonary embolism. The primary focus is on assessing the diagnostic performance of ultrasound-guided measures of right ventricular dilation and strain. Additionally, the study will explore the effectiveness of combining these ultrasound measures with the pulmonary embolism severity index (PESI) score to enhance outcome predictions. By identifying at-risk patients, the study aims to improve treatment decisions regarding hospitalization or outpatient care.
Why it matters
Potential benefit: If successful, this study could lead to more accurate predictions of adverse outcomes in pulmonary embolism patients, potentially allowing for safer outpatient treatment options.
How similar studies have gone: Other studies have shown promise in using ultrasound for predicting outcomes in pulmonary embolism, but this specific approach combining echocardiography with PESI is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>= 18 years of age * ED diagnosis of acute pulmonary embolism with identification on CT imaging Exclusion Criteria: * Age \<18 years of age * Inability to provide informed consent * Incarceration * Current PE previously diagnosed prior to index ED visit
Where it's running
-
Wellspan York Hospital
York, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Brent A Becker, MD — WellSpan Health
- Study coordinator: Brent A Becker, MD
- Email: bbecker2@wellspan.org
- Phone: 717 851 4819
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.