Using ultrasound to predict outcomes in emergency patients with pulmonary embolism
Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism
WellSpan Health · NCT05050617
This study is testing whether using ultrasound in the emergency room can help doctors predict how well patients with pulmonary embolism will do in the short term.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | WellSpan Health (other) |
| Locations | 1 site (York, Pennsylvania) |
| Trial ID | NCT05050617 on ClinicalTrials.gov |
What this trial studies
This observational study examines how point-of-care echocardiography can predict short-term adverse outcomes in emergency department patients diagnosed with acute pulmonary embolism. The primary focus is on assessing the diagnostic performance of ultrasound-guided measures of right ventricular dilation and strain. Additionally, the study will explore the effectiveness of combining these ultrasound measures with the pulmonary embolism severity index (PESI) score to enhance outcome predictions. By identifying at-risk patients, the study aims to improve treatment decisions regarding hospitalization or outpatient care.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with acute pulmonary embolism confirmed by CT imaging.
Not a fit: Patients under 18 years of age, those unable to provide informed consent, or individuals with a prior diagnosis of pulmonary embolism may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate predictions of adverse outcomes in pulmonary embolism patients, potentially allowing for safer outpatient treatment options.
How similar studies have performed: Other studies have shown promise in using ultrasound for predicting outcomes in pulmonary embolism, but this specific approach combining echocardiography with PESI is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>= 18 years of age * ED diagnosis of acute pulmonary embolism with identification on CT imaging Exclusion Criteria: * Age \<18 years of age * Inability to provide informed consent * Incarceration * Current PE previously diagnosed prior to index ED visit
Where this trial is running
York, Pennsylvania
- Wellspan York Hospital — York, Pennsylvania, United States (RECRUITING)
Study contacts
- Principal investigator: Brent A Becker, MD — WellSpan Health
- Study coordinator: Brent A Becker, MD
- Email: bbecker2@wellspan.org
- Phone: 717 851 4819
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Embolism