Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using ultrasound to predict outcomes in emergency patients with pulmonary embolism

Official title: Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism

Run by WellSpan Health · NCT05050617 · Data updated 2026-11-12

This study is testing whether using ultrasound in the emergency room can help doctors predict how well patients with pulmonary embolism will do in the short term.

More Pulmonary Embolism trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment250 (estimated)
SponsorWellSpan Health
Academic / other
Locations1 site (York, Pennsylvania)
StatusRecruiting
StartedSeptember 9, 2021
Main results expectedSeptember 2026
Study endsDecember 2026
Registry record updatedJune 3, 2026
Trial IDNCT05050617 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who have been diagnosed with acute pulmonary embolism confirmed by CT imaging.

Probably not a fit

Patients under 18 years of age, those unable to provide informed consent, or individuals with a prior diagnosis of pulmonary embolism may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines how point-of-care echocardiography can predict short-term adverse outcomes in emergency department patients diagnosed with acute pulmonary embolism. The primary focus is on assessing the diagnostic performance of ultrasound-guided measures of right ventricular dilation and strain. Additionally, the study will explore the effectiveness of combining these ultrasound measures with the pulmonary embolism severity index (PESI) score to enhance outcome predictions. By identifying at-risk patients, the study aims to improve treatment decisions regarding hospitalization or outpatient care.

Why it matters

Potential benefit: If successful, this study could lead to more accurate predictions of adverse outcomes in pulmonary embolism patients, potentially allowing for safer outpatient treatment options.

How similar studies have gone: Other studies have shown promise in using ultrasound for predicting outcomes in pulmonary embolism, but this specific approach combining echocardiography with PESI is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>= 18 years of age
* ED diagnosis of acute pulmonary embolism with identification on CT imaging

Exclusion Criteria:

* Age \<18 years of age
* Inability to provide informed consent
* Incarceration
* Current PE previously diagnosed prior to index ED visit

Where it's running

  • Wellspan York Hospital
    York, Pennsylvania, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.