Using ultrasound to predict kidney injury in sepsis patients
Prediction of Acute Kidney Injury in Patients With Sepsis Using Venous Excess Ultrasound Score
Mansoura University · NCT06176807
This study is testing whether an ultrasound method can help doctors spot kidney injury early in adults with sepsis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 21 Years to 65 Years |
| Sex | All |
| Sponsor | Mansoura University (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Mansoura) |
| Trial ID | NCT06176807 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the risk of acute kidney injury in patients with sepsis by utilizing the Venous Excess Ultrasound Score (VExUS). It focuses on patients who meet specific criteria for sepsis and evaluates their condition based on ultrasound measurements of the inferior vena cava (IVC) to determine levels of venous congestion. The study will include patients aged 21 to 65 who present with sepsis symptoms and risk factors, while excluding those with certain pre-existing conditions. The findings could help in early identification and management of kidney injury in critically ill patients.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 21 to 65 who are diagnosed with sepsis and meet specific clinical criteria.
Not a fit: Patients with renal failure, right ventricular dysfunction, or other specified exclusions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved early detection and management of acute kidney injury in sepsis patients, potentially reducing mortality rates.
How similar studies have performed: While the use of ultrasound in assessing venous congestion is established, the specific application of VExUS in predicting acute kidney injury in sepsis is a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients with sepsis. * Patients aged between 21 and 65. * Both sexes Exclusion Criteria: * Patients refused to participate in the study. * Renal failure. * Right ventricular dysfunction and dilatation. * Moderate to severe tricuspid regurge. * Cases of cirrhosis with liver cell failure. * Inadequate window. * IVC thrombus
Where this trial is running
Mansoura
- Nevert adel — Mansoura, Egypt (RECRUITING)
Study contacts
- Study coordinator: yahya m wahba, MD
- Email: wahbayahya2007@mans.edu.eg
- Phone: 01211313554
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Intensive Care Unit