Using ultrasound to improve diagnosis of oral cancer
Intraoral Ultra-High Frequency Ultrasound of Oral Soft Tissue Lesions
This study is testing a new ultrasound technique to see if it can help doctors better diagnose oral cancer in patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Pisa Academic / other |
| Locations | 1 site (Pisa) |
| Trial ID | NCT06336941 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance the diagnostic process for oral squamous cell carcinoma by utilizing ultra-high frequency intraoral ultrasonography. The approach focuses on providing a minimally invasive imaging technique that can visualize anatomical structures beyond the mucosal surface, which is currently a limitation in standard clinical examinations. By integrating this advanced ultrasound technology into routine diagnostics, the study seeks to improve the accuracy and efficiency of identifying oral neoplasms. The methodology involves clinical diagnosis confirmation and eligibility for surgical treatment as key criteria for participant selection.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with a clinical diagnosis of oral squamous cell carcinoma who are eligible for surgical treatment.
Not a fit: Patients with oral lesions other than oral squamous cell carcinoma or those with uncontrolled chronic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this technique could lead to earlier and more accurate diagnoses of oral cancer, potentially improving patient outcomes.
How similar studies have performed: While there have been attempts to use ultrasonography in similar contexts, this specific application of ultra-high frequency intraoral ultrasound is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of oral squamous cell carcinoma * Eligibility for surgical treatment * Acceptance to be included in the study Exclusion Criteria: * Oral lesions other than oral squamous cell carcinoma * Pregnant or breastfeeding patients * Uncontrolled chronic diseases and/or conditions hindering the participation in the study * Denial of inclusion in the study
Where this trial is running
Pisa
- Università di Pisa — Pisa, Italy (Recruiting)
Study contacts
- Study coordinator: Rossana Izzetti, DDS, PhD
- Email: rossana.izzetti@unipi.it
- Phone: +39050993037
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.