Using ultrasound to improve diagnosis of oral cancer
Official title: Intraoral Ultra-High Frequency Ultrasound of Oral Soft Tissue Lesions
Run by University of Pisa · NCT06336941 · Data updated 2026-11-12
This study is testing a new ultrasound technique to see if it can help doctors better diagnose oral cancer in patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | University of Pisa Academic / other |
| Locations | 1 site (Pisa) |
| Status | Recruiting |
| Started | June 7, 2018 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2030 |
| Registry record updated | February 25, 2026 |
| Trial ID | NCT06336941 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals with a clinical diagnosis of oral squamous cell carcinoma who are eligible for surgical treatment.
✕Probably not a fit
Patients with oral lesions other than oral squamous cell carcinoma or those with uncontrolled chronic diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance the diagnostic process for oral squamous cell carcinoma by utilizing ultra-high frequency intraoral ultrasonography. The approach focuses on providing a minimally invasive imaging technique that can visualize anatomical structures beyond the mucosal surface, which is currently a limitation in standard clinical examinations. By integrating this advanced ultrasound technology into routine diagnostics, the study seeks to improve the accuracy and efficiency of identifying oral neoplasms. The methodology involves clinical diagnosis confirmation and eligibility for surgical treatment as key criteria for participant selection.
Why it matters
Potential benefit: If successful, this technique could lead to earlier and more accurate diagnoses of oral cancer, potentially improving patient outcomes.
How similar studies have gone: While there have been attempts to use ultrasonography in similar contexts, this specific application of ultra-high frequency intraoral ultrasound is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of oral squamous cell carcinoma * Eligibility for surgical treatment * Acceptance to be included in the study Exclusion Criteria: * Oral lesions other than oral squamous cell carcinoma * Pregnant or breastfeeding patients * Uncontrolled chronic diseases and/or conditions hindering the participation in the study * Denial of inclusion in the study
Where it's running
-
Università di Pisa
Pisa, Italy Recruiting
Study contacts
- Study coordinator: Rossana Izzetti, DDS, PhD
- Email: rossana.izzetti@unipi.it
- Phone: +39050993037
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.