Using ultrasound to improve diagnosis of nerve disorders like GBS and CIDP

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of neuromuscular ultrasound (NMUS) to detect nerve alterations in patients with Guillain-Barré Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). By performing serial nerve ultrasounds and nerve conduction studies (NCS), the researchers aim to determine if ultrasound findings correlate with electrodiagnostic results, which could aid in early diagnosis and intervention. The study focuses on differentiating between axonal and demyelinating subtypes of these conditions, potentially improving patient outcomes through better understanding and management of the diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosis of patient group:

   * GBS Patients: Diagnosed according to the criteria of the National Institute of Neurological Disorders and Stroke (NINDS) and the Brighton Collaboration (2011).
   * CIDP Patients: Diagnosed according to the criteria of the European Federation of Neurological Societies/Peripheral Nerve Society (EFNS/PNS).
2. Age: Participants aged 18 to 75 years.
3. Onset:

   * GBS Patients: Recent onset of GBS within the first 2 weeks of symptom onset.
   * CIDP Patients: Either relapsing or progressive course consistent with CIDP diagnosis.
4. Gender: Both male and female participants are eligible.
5. Participation: Willingness to participate in the study, including undergoing disease-related examinations and assessments.
6. Consent: Ability and willingness to provide informed consent

Exclusion Criteria:

1. Patients unable or unwilling to provide informed consent.
2. Patients with metabolic disorders or malignancies.
3. Patients with other causes of peripheral neuropathy.
4. Patients with other causes of acute flaccid paralysis.

Where it's running

• Assiut University Hospitals
  Asyut, Egypt Recruiting

Study contacts

• Study coordinator: Mohammed Gad Ibrahim, MB, BCh
• Email: modyurd222@gmail.com
• Phone: +201022748859

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.