Using ultra-low field MRI to assess brain conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of an ultra-low field MRI (ULF-MRI) system in detecting neurological disorders compared to standard MRI techniques. Participants aged 3 years and older, including both healthy individuals and those with neurological symptoms, will undergo two MRI exams: one standard and one ULF-MRI. The study will analyze the sensitivity of ULF-MRI in identifying brain pathologies and will also collect data on participants' social determinants of health. The ultimate goal is to enhance access to neuroimaging and improve early intervention strategies for neurological diseases.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

* Stated willingness to comply with all study procedures and availability for the duration of the study.
* Volunteer of any gender, 3 years of age and older.
* Adult participant: must be capable of understanding the procedures and requirements of this study and be able and willing to sign an informed consent document.
* Minor participant: Must have a parent or guardian capable of understanding the procedures and requirements of this study who are willing to sign an informed parental consent document, and where feasible, the minor age 7 and older provides assent.
* Either:

  * Adult in good general health as evidenced by medical history or
  * Diagnosed with a stroke, a neurological or neuro-oncological disease, or
  * Exhibiting symptoms suggestive of neurological or neuro-oncological disease.

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

* Unable to undergo MRI study based on screening (e.g., presence of non-MRI compatible objects).
* Pregnancy or lactation, if contrast agent is required.

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Silvina G Horovitz, Ph.D. — National Institute of Neurological Disorders and Stroke (NINDS)
• Study coordinator: Ruli Zhang
• Email: zhangr@ninds.nih.gov
• Phone: (301) 435-6028

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.