Using thermal ablation to improve cervical cancer prevention in Kenya
Implementation and Scale Up of a Single-visit, Screen-and-treat Approach With Thermal Ablation for Sustainable Cervical Cancer Prevention Services in Kenya
NA · University of Washington · NCT05472311
This study is testing a new way to prevent cervical cancer in Kenya by combining screening and treatment in one visit using thermal ablation to see if it helps more women get the care they need.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 565 (estimated) |
| Ages | 21 Years to 60 Years |
| Sex | All |
| Sponsor | University of Washington (other) |
| Locations | 1 site (Thika, Kiambu County) |
| Trial ID | NCT05472311 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to implement a single-visit screen-and-treat approach combined with thermal ablation for cervical cancer prevention in Kenya. The study will take place in 10 reproductive health clinics and will evaluate the effectiveness of this method using a mixed-methods approach based on the RE-AIM framework. By addressing the challenges of low screening and treatment rates, the trial seeks to enhance the delivery of cervical cancer prevention services in low-resource settings. The intervention is designed to be sustainable and scalable, leveraging local healthcare providers and resources.
Who should consider this trial
Good fit: Ideal candidates for this study include women aged 25-60 who are seeking cervical cancer screening services and have screened positive for pre-cancer lesions.
Not a fit: Patients who decline to participate or do not meet the eligibility criteria will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly increase the rates of cervical cancer screening and treatment, ultimately reducing the incidence and mortality of cervical cancer in low-income settings.
How similar studies have performed: Preliminary data from similar approaches in Zambia and Kenya have shown success with thermal ablation, indicating potential for this method in cervical cancer prevention.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Policy makers * Health facility managers * Health care providers at participating reproductive health clinics * Women seeking cervical cancer screening services * Women who screen positive for pre-cancer lesion of the cervix * Consent to study participation * Age 25-60 years * Women seeking cervical cancer screening services at participating RH clinics * Health care providers providing cervical cancer prevention services at participating RH clinics Exclusion Criteria: -Any individual who declines to participate or have their data collected for purpose of research
Where this trial is running
Thika, Kiambu County
- Phrd-Ccr-Kemri — Thika, Kiambu County, Kenya (RECRUITING)
Study contacts
- Principal investigator: Nelly Mugo, MPH, MMed — University of Washington
- Study coordinator: Lynda Oluoch, MBChB, MPH
- Email: lynda@pipsthika.org
- Phone: 206-520-3866
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cervical Cancer, invasive cervical cancer, cervical intra-epithelial lesion, human papillomavirus, single visit screen- and - treat, thermal ablation, implementation science