Using thermal ablation to improve cervical cancer prevention in Kenya
Official title: Implementation and Scale Up of a Single-visit, Screen-and-treat Approach With Thermal Ablation for Sustainable Cervical Cancer Prevention Services in Kenya
Run by University of Washington · NCT05472311 · Data updated 2026-11-12
This study is testing a new way to prevent cervical cancer in Kenya by combining screening and treatment in one visit using thermal ablation to see if it helps more women get the care they need.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 60 Years |
| Sex | All |
| Enrollment | 565 (estimated) |
| Sponsor | University of Washington Academic / other |
| Locations | 1 site (Thika, Kiambu County) |
| Status | Recruiting |
| Started | May 17, 2022 |
| Main results expected | April 26, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | August 19, 2024 |
| Trial ID | NCT05472311 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study include women aged 25-60 who are seeking cervical cancer screening services and have screened positive for pre-cancer lesions.
✕Probably not a fit
Patients who decline to participate or do not meet the eligibility criteria will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to implement a single-visit screen-and-treat approach combined with thermal ablation for cervical cancer prevention in Kenya. The study will take place in 10 reproductive health clinics and will evaluate the effectiveness of this method using a mixed-methods approach based on the RE-AIM framework. By addressing the challenges of low screening and treatment rates, the trial seeks to enhance the delivery of cervical cancer prevention services in low-resource settings. The intervention is designed to be sustainable and scalable, leveraging local healthcare providers and resources.
Why it matters
Potential benefit: If successful, this approach could significantly increase the rates of cervical cancer screening and treatment, ultimately reducing the incidence and mortality of cervical cancer in low-income settings.
How similar studies have gone: Preliminary data from similar approaches in Zambia and Kenya have shown success with thermal ablation, indicating potential for this method in cervical cancer prevention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Policy makers * Health facility managers * Health care providers at participating reproductive health clinics * Women seeking cervical cancer screening services * Women who screen positive for pre-cancer lesion of the cervix * Consent to study participation * Age 25-60 years * Women seeking cervical cancer screening services at participating RH clinics * Health care providers providing cervical cancer prevention services at participating RH clinics Exclusion Criteria: -Any individual who declines to participate or have their data collected for purpose of research
Where it's running
-
Phrd-Ccr-Kemri
Thika, Kiambu County, Kenya Recruiting
Study contacts
- Principal investigator: Nelly Mugo, MPH, MMed — University of Washington
- Study coordinator: Lynda Oluoch, MBChB, MPH
- Email: lynda@pipsthika.org
- Phone: 206-520-3866
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.