Using tendon transfers to repair massive rotator cuff tears

Tendon Transfer Techniques for Massive Rotator Cuff Tear Repairs: An Integrated Prospective Randomized Multicenter Trial

Not applicable Interventional University of Maryland, Baltimore · NCT04588506

This study is testing which of two surgical techniques for repairing large rotator cuff tears helps people feel better and recover more effectively.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment84 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Maryland, Baltimore Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT04588506 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of different tendon transfer techniques to repair massive tears of the rotator cuff muscles in the shoulder. It involves a prospective randomized design with 84 participants, comparing outcomes between the Latissimus dorsi and Lower trapezius tendon transfer techniques. The study aims to determine which technique yields better patient-reported outcomes for individuals with irreparable rotator cuff tears. Participants will be randomly assigned to one of the two intervention groups.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 with massive, irreparable posterior-superior rotator cuff tears and minimal glenohumeral arthritis.

Not a fit: Patients with severe glenohumeral arthritis, prior tendon transfers, or specific shoulder conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide clearer guidance on the most effective surgical technique for repairing massive rotator cuff tears, potentially improving patient recovery and outcomes.

How similar studies have performed: There are currently no studies that have definitively shown which tendon transfer technique is superior for this condition, making this approach novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects must have massive, irreparable tear of the posterior-superior rotator cuff
* Subjects between 18 years and 65 years (≥ 18 and ≤ 65 years of age).
* Diagnosis of no to minimal glenohumeral arthritis- Hamada 1 and 2
* Subject with irreparable subscapularis tendon tear (Arms 3 and 4 ONLY)

Exclusion Criteria:

* Subjects having severe glenohumeral arthritis
* History of prior tendon transfer
* Axillary nerve injury
* Deltoid deficiency
* Subjects with pseudo paralysis
* History of post-operative deep shoulder infection
* Non-English-speaking subjects.
* Subject has any condition, that in the opinion of the investigator, would prevent them from completing this study
* Subject with irreparable subscapularis tendon tear (Arms 1 and 2 ONLY)

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Rotator Cuff TearsMassive Rotator Cuff TearsTendon TransferTendon Transfer Techniques
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.