Using super-oxidized solution for treating secondary peritonitis during emergency surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of peritoneal lavage with super-oxidized solution (SOS) compared to the standard Ringer's solution in patients undergoing emergency abdominal surgery for secondary peritonitis. Secondary peritonitis is a serious condition that can lead to high rates of morbidity and mortality due to surgical site infections and sepsis. The study aims to determine if SOS can reduce the incidence of surgical site infections and mortality in this patient population. Eligible patients will be randomized during surgery to receive either SOS or Ringer's solution as part of their treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Secondary peritonitis due to suspected hollow viscus perforation, anastomotic insufficiency, and/or abdominal abscess (including patients with the named abdominal emergencies as a complication after elective surgery)
* Scheduled emergency abdominal surgery by laparotomy with peritoneal lavage
* Age over 18 years
* Written informed consent

Exclusion Criteria

* Pregnancy (will be ruled out using beta-hCG testing in women of childbearing potential)
* Patients with primary or tertiary peritonitis

Where it's running

• Inselspital, Bern University Hospital
  Bern, Switzerland Recruiting

Study contacts

• Principal investigator: Tobias Haltmeier, MD — Inselspital, Bern University Hospital
• Study coordinator: Tobias Haltmeier, MD
• Email: tobias.haltmeier@insel.ch
• Phone: +41 31 664 03 04

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• Personalized treatment with Pentaglobin® for patients with peritonitis after surgery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.