Using stem cells to treat various chronic and acute health conditions
Official title: Evaluation of the Safety, Tolerability and Efficacy of Regenerative Therapy for the Treatment of Various Chronic and Acute Conditions
Run by Thomas Advanced Medical LLC · NCT04684602 · Data updated 2026-11-12
This study is testing if stem cell therapy can help people with different long-term and short-term health issues, like autoimmune diseases and heart problems, feel better and improve their quality of life.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Thomas Advanced Medical LLC Industry-sponsored |
| Locations | 1 site (Culver City, California) |
| Status | Recruiting |
| Started | July 9, 2020 |
| Main results expected | July 9, 2030 |
| Study ends | December 9, 2030 |
| Registry record updated | April 29, 2022 |
| Trial ID | NCT04684602 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who can provide informed consent and are available for follow-up visits.
✕Probably not a fit
Patients with active or recent malignancy, those who are pregnant or breastfeeding, or individuals unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multi-arm, multi-site study evaluates the safety, tolerability, and efficacy of stem cell therapy for a range of acute and chronic conditions, including autoimmune diseases, cardiovascular disorders, and diabetes complications. The study is designed to gather clinical outcomes using various validated instruments that assess both general quality of life and condition-specific metrics. Participants will receive treatments with PrimePro™ or PrimeMSK™ stem cell therapies, with follow-up visits to monitor their progress and response to treatment.
Why it matters
Potential benefit: If successful, this study could provide new treatment options for patients suffering from a variety of chronic and acute conditions.
How similar studies have gone: Other studies have shown promising results with stem cell therapies for various conditions, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 and older * Ability to provide informed consent * Availability for follow up visits Exclusion Criteria: * Active or recent malignancy (within last 2 years) * Pregnancy or breast-feeding * Inability to provide informed consent
Where it's running
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Southern California Hospital at Culver City / Southern California Hospital at Hollywood / Multiple US-based Sub-Investigator Sites
Culver City, California, United States Recruiting
Study contacts
- Principal investigator: Ernst R Von Schwarz, MD, PhD — HeartStem Institute, Southern California Hospital at Culver City
- Study coordinator: Paul C Bogaardt, PhD(c), MSc, MBA
- Email: paul@thomasadvancedmedical.com
- Phone: 866 864 7789
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.