Using Stellate Ganglion Block to Prevent Depression After Mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of stellate ganglion block as a preventive measure against post-mastectomy depression in female breast cancer patients. The study focuses on patients undergoing unilateral modified radical mastectomy, aiming to reduce the incidence of chronic pain and depression that can follow this surgery. By administering a stellate ganglion block, the trial seeks to evaluate its effectiveness in alleviating psychological distress and pain associated with the surgical procedure. The approach is based on previous applications of this technique in treating PTSD and depression symptoms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female patients
* Age ranging from 18 to 65 years
* American Society of Anesthesiologists (ASA) no more than II
* Had unilateral cancer breast
* Scheduled to do unilateral modified radical mastectomy

Exclusion Criteria:

* Pregnant female
* Existing Horner syndrome
* Had any neuromuscular disease
* Had allergy to local anesthetics
* History of use of analgesics
* Had any deformity or a previous surgery in the neck or ipsilateral arm or breast
* Had any contraindication to the procedure (coagulation disorders, local infection, sepsis)
* Had any contraindication to the sympathetic blockade (decompensate cardiopulmonary or hemodynamic disorders)
* History of psychotic disorder including depression, bipolar disorder or personality disorder
* Patient with Beck Depression Inventory (BDI) score more than 13

Where it's running

• Maha
  Al Mansurah, Egypt Recruiting

Study contacts

• Study coordinator: Maha Abo-Zeid, MD
• Email: mahazed@mans.edu.eg
• Phone: 01019216192

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.