Using special lenses to slow down myopia in children
Effectiveness of the Defocus Incorporated Spectacle Lenses on Fast Progressing Myope - Auxiliary Group
This study tests if special lenses can help slow down worsening eyesight in children with myopia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 59 (estimated) |
| Ages | 4 Years to 12 Years |
| Sex | All |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hung Hom) |
| Trial ID | NCT05888805 on ClinicalTrials.gov |
What this trial studies
This study examines the effectiveness of Defocus Incorporated Multiple Segments (DIMS) spectacle lenses in controlling the progression of myopia in children who experience rapid worsening of their eyesight. Participants will receive DIMS lenses, which are designed to create myopic defocus images while correcting distance vision. Their eye measurements, including cycloplegic refraction and axial length, will be monitored every six months over a two-year period to assess the lenses' impact on myopia progression.
Who should consider this trial
Good fit: Ideal candidates are children with a documented history of fast progressing myopia, characterized by specific refractive error and axial length criteria.
Not a fit: Patients with strabismus, binocular vision abnormalities, or those with prior myopia control experiences may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly slow down the worsening of myopia in children, potentially reducing the risk of severe vision problems later in life.
How similar studies have performed: Other studies have shown promising results with similar multifocal lens approaches for myopia control, indicating potential for success in this study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * SER: -1.00D or below * Documented history of fast progressing myopia, either in SER or AL * SER progression: 0.50D/year or more * AL elongation: 0.27mm/year or more * Best-corrected monocular visual acuity (VA) in both eyes: 0.00 logMAR (equivalent) or better * Acceptance of random group allocation and the masked study design * Anisometropia of 1.50 D or less * Astigmatism of 2.00 D or less Exclusion Criteria: * Strabismus and binocular vision abnormalities * Ocular and systemic abnormalities * Prior experience of myopia control
Where this trial is running
Hung Hom
- School of Optometry, The Hong Kong Polytechnic University — Hung Hom, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Dennis Yan Yin Tse, PhD — School of Optometry, The Hong Kong Polytechnic University
- Study coordinator: Dennis Yan Yin Tse, PhD
- Email: dennis.tse@polyu.edu.hk
- Phone: 852-27666096
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.