Using special lenses to control myopia in children
The Influence of Baseline Relative Peripheral Refraction in Myopia Control Using Myopic Defocus
This study is testing special lenses to see if they can help slow down the worsening of nearsightedness in children aged 6 to 9 years.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 6 Years to 9 Years |
| Sex | All |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT06161311 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of Defocus Incorporated Multiple Segments (DIMS) spectacle lenses in controlling myopia progression in children aged 6 to 9 years. The study focuses on understanding how baseline relative peripheral refraction (RPR) may influence the efficacy of these lenses in slowing down myopia. By examining the relationship between peripheral and central refraction, researchers aim to determine the optimal amount of myopic defocus needed for effective myopia control. The trial will include children with specific refractive errors and visual acuity criteria, while excluding those with certain ocular or systemic conditions.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 6 to 9 years with myopia ranging from -0.75 to -5.00 Diopters.
Not a fit: Patients with ocular or systemic abnormalities that could affect visual functions or those who have previously used myopia control treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the progression of myopia in children, potentially preventing severe vision impairment later in life.
How similar studies have performed: Previous studies have shown that DIMS lenses can effectively slow myopia progression, indicating a promising approach in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age at enrolment: 6-9 years * Spherical equivalent refraction (SER): -0.75 to -5.00 Diopters (D) * Astigmatism: -1.50 D or less * Anisometropia: 1.50 D or less * Spectacle best-corrected monocular visual acuity (VA): 0.00 logMAR or better Exclusion Criteria: * Ocular and systemic abnormalities might affect visual functions or refractive development * Prior use of any drugs or optical devices of myopia control treatment.
Where this trial is running
Hong Kong
- Optometry Research Clinic — Hong Kong, Hong Kong (Recruiting)
Study contacts
- Study coordinator: Tsz Wing Leung, PhD
- Email: jeffrey.TW.leung@polyu.edu.hk
- Phone: 27664268
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.