Using simvastatin to protect the heart during cardiac surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the myocardial protection effects of simvastatin in patients undergoing cardiac surgery for congenital heart disease and isolated heart valve disease. The research aims to determine whether simvastatin can reduce myocardial injury and improve cardiac function during and after surgery, particularly in cases involving cardiopulmonary bypass. Conducted at two medical centers, this interventional study will assess the long-term benefits of simvastatin postoperatively.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* More than 18-year-old,
* Congenital heart disease(not complex),
* Isolated heart valve disease,

Exclusion Criteria:

* Coronary artery disease
* Allergy for statins
* Poor liver function,Hepatitis
* Gestation women and Breast-feeding women

Where it's running

• The First Affiliated Hospital, Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Principal investigator: Jing-song Ou, MD,PhD — The Frist Affiliated Hospital, Sun Yat-sen University
• Study coordinator: Jing-song Ou, MD, PhD
• Email: oujs2000@yahoo.com
• Phone: 8620-87755766

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.