Using Shear Wave Elastography to Identify Acute Kidney Injury
The Biosonographic Index - A Novel Index for the Early Detection of Acute Kidney Injury After Vascular Surgery - an Exploratory Study.
This study is testing a new imaging technique to see if it can help identify kidney injury in people who have had vascular surgery compared to healthy individuals.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Trial ID | NCT04144894 on ClinicalTrials.gov |
What this trial studies
This exploratory study investigates the application of Shear Wave Elastography to distinguish between Acute Kidney Injury following vascular surgery and healthy individuals. The study aims to assess the effectiveness of this imaging technique in identifying kidney conditions that may not be apparent through traditional methods. Participants will undergo non-invasive imaging to evaluate kidney health and function. The findings could enhance diagnostic accuracy for patients at risk of kidney injury.
Who should consider this trial
Good fit: Ideal candidates for this study are adults without a history of diabetes or hypertension, with normal kidney structure and function.
Not a fit: Patients with end-stage renal disease, significant comorbidities, or those undergoing emergency procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to earlier and more accurate diagnosis of Acute Kidney Injury, improving patient outcomes.
How similar studies have performed: While the use of Shear Wave Elastography is a novel approach in this context, similar imaging techniques have shown promise in other areas of medical diagnostics.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * No history of diabetes or hypertension * Estimated Glomerular Filtration Rate \> 60 ml/min/m\^2 * Structurally normal kidney on renal ultrasound * BMI \< 27 kg/m\^2 Exclusion Criteria: * Prisoners directly admitted from a correctional facility * Children \< 19 years or under 50 kg body weight if age is unknown * Patients with end stage renal disease or preexisting glomerular filtration rate less than or equal to 30 mL/min/1.73 m\^2 or need for dialysis * Patients with end stage heart disease on the cardiac transplant list * Patients undergoing procedures without vascular surgery * All transplant patients * Patients on ventricular assist devices * Patients undergoing emergency procedures * Patients with body mass index \> 27kg/m\^2 * Any condition that would impede visualization of the kidneys by ultrasound
Where this trial is running
Birmingham, Alabama
- University of Alabama at Birmingham — Birmingham, Alabama, United States (Recruiting)
Study contacts
- Principal investigator: Ahmed Zaky, MD, MPH — University of Alabama at Birmingham
- Study coordinator: Adam B Sturdivant, MPH
- Email: Adamsturdivant@uabmc.edu
- Phone: 205-934-4042
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.