Using Shear Wave Elastography to Identify Acute Kidney Injury
Official title: The Biosonographic Index - A Novel Index for the Early Detection of Acute Kidney Injury After Vascular Surgery - an Exploratory Study.
Run by University of Alabama at Birmingham · NCT04144894 · Data updated 2026-11-12
This study is testing a new imaging technique to see if it can help identify kidney injury in people who have had vascular surgery compared to healthy individuals.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 19 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | January 15, 2020 |
| Main results expected | October 15, 2026 |
| Study ends | December 2, 2026 |
| Registry record updated | September 19, 2025 |
| Trial ID | NCT04144894 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults without a history of diabetes or hypertension, with normal kidney structure and function.
✕Probably not a fit
Patients with end-stage renal disease, significant comorbidities, or those undergoing emergency procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This exploratory study investigates the application of Shear Wave Elastography to distinguish between Acute Kidney Injury following vascular surgery and healthy individuals. The study aims to assess the effectiveness of this imaging technique in identifying kidney conditions that may not be apparent through traditional methods. Participants will undergo non-invasive imaging to evaluate kidney health and function. The findings could enhance diagnostic accuracy for patients at risk of kidney injury.
Why it matters
Potential benefit: If successful, this approach could lead to earlier and more accurate diagnosis of Acute Kidney Injury, improving patient outcomes.
How similar studies have gone: While the use of Shear Wave Elastography is a novel approach in this context, similar imaging techniques have shown promise in other areas of medical diagnostics.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * No history of diabetes or hypertension * Estimated Glomerular Filtration Rate \> 60 ml/min/m\^2 * Structurally normal kidney on renal ultrasound * BMI \< 27 kg/m\^2 Exclusion Criteria: * Prisoners directly admitted from a correctional facility * Children \< 19 years or under 50 kg body weight if age is unknown * Patients with end stage renal disease or preexisting glomerular filtration rate less than or equal to 30 mL/min/1.73 m\^2 or need for dialysis * Patients with end stage heart disease on the cardiac transplant list * Patients undergoing procedures without vascular surgery * All transplant patients * Patients on ventricular assist devices * Patients undergoing emergency procedures * Patients with body mass index \> 27kg/m\^2 * Any condition that would impede visualization of the kidneys by ultrasound
Where it's running
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University of Alabama at Birmingham
Birmingham, Alabama, United States Recruiting
Study contacts
- Principal investigator: Ahmed Zaky, MD, MPH — University of Alabama at Birmingham
- Study coordinator: Adam B Sturdivant, MPH
- Email: Adamsturdivant@uabmc.edu
- Phone: 205-934-4042
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.