Using sesame oil to prevent phlebitis in cancer patients with catheters

Effects of Topical Sesame Oil in the Prevention of Chemotherapy-associated Peripheral Venous Catheter Phlebitis: Clinical Trial.

NA · Hospital Universitario Marqués de Valdecilla · NCT06375850

This study is testing if applying sesame oil can help prevent vein inflammation in cancer patients who need catheters for chemotherapy.

Quick facts

PhaseNA
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Universitario Marqués de Valdecilla (other)
Drugs / interventionschemotherapy
Locations1 site (Santander, Cantabria)
Trial IDNCT06375850 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effects of topical sesame oil in preventing phlebitis, an inflammation of the veins, in patients undergoing chemotherapy for neoplasms. The study focuses on patients who require peripheral venous catheters for drug administration, as these catheters can lead to phlebitis due to chemical, mechanical, and infectious factors. Participants will receive either sesame oil or a saline solution to assess the effectiveness of sesame oil in reducing the incidence of phlebitis.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old diagnosed with a neoplasm requiring chemotherapy and who have a central venous catheter in place.

Not a fit: Patients with allergies to sesame oil or nuts, or those in palliative care, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the pain and complications associated with phlebitis in cancer patients receiving chemotherapy.

How similar studies have performed: While the use of sesame oil is a novel approach, similar studies have shown that topical treatments can effectively reduce phlebitis in various patient populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be over 18 years of age.
* To be conscious and have a cognitive state that allows him/her to give consent to participate in the study.
* Be diagnosed with a neoplasm that requires chemotherapy treatment.
* To be a carrier of a CVP in the upper extremity as vascular access for chemotherapy administration.

Exclusion Criteria:

* Being allergic to sesame oil.
* Be allergic to nuts.
* Not being able to speak, read and write in Spanish.
* Last days or palliative situation.

Where this trial is running

Santander, Cantabria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Phlebitis, Neoplasms, Antineoplastic Agents, Sesame Oil, Catheterization, Peripheral

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.