Using rTMS to treat spasticity in children with cerebral palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of repetitive transcranial magnetic stimulation (rTMS) on children with hemiplegic cerebral palsy. Participants will receive 10 days of rTMS treatment followed by intensive training of the impaired limb, with assessments of spasticity and neurophysiological changes through MRI scans. The study aims to compare the outcomes of the rTMS group with a sham group to determine the efficacy of this non-invasive treatment in improving motor function. The goal is to provide a new therapeutic option for managing spasticity in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged between 4 years and 18 years
* Diagnosis of hemiplegia
* Upper limb spasticity ≥ 1
* IQ ≥ 50

Exclusion Criteria:

* Any contra-indications to rTMS
* Severe spasticity (score of 4 or more in Ashworth scale)
* Uncontrollable epilepsy
* History of Botulinum toxin A injection in previous 6 months
* Upper limb casting in previous 6 months

Where it's running

• Li Ka Shing Faculty of Medicine
  Hong Kong, Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Winnie Wan Yee Tso, MBBS
• Email: wytso@hku.hk
• Phone: +85222554295

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Immersive multisensory action observation and motor imagery for children and young adults with cerebral palsy and typical development

  This pilot will test whether adding sound and touch to action observation and motor imagery increases mirror-neuron system activation in children and young adults with cerebral palsy and in typically developing peers.

  Recruiting IRCCS Fondazione Stella Maris · Calambrone, Pisa · NCT07369193

• Improving oral motor skills in children with cerebral palsy using a specific method

  This study is testing a new method to see if it can help young children with cerebral palsy improve their eating skills and manage drooling better.

  Recruiting Cairo University · Giza · NCT06838403

• Hand and Bimanual Therapy in a VR game for children with cerebral palsy

  This study tests whether a VR-based hand therapy program called HABIT-VR can improve hand function in children aged 6–17 with cerebral palsy, compared to a standard VR HABIT-VR approach.

  Recruiting University of Nebraska · Omaha, Nebraska · NCT06818877

• Evaluating the effects of a single session of robotic gait training with Trexo

  This study is testing how a single session of robotic walking training with the Trexo device can help people with physical disabilities, like cerebral palsy, improve their walking ability and overall activity.

  Recruiting University of Calgary · Calgary, Alberta · NCT06407219

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.