Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using routine data to improve diagnosis of sepsis and septic shock

Official title: Evaluation of Parameters Collected From Routine Data for the Diagnosis of Sepsis and Septic Shock and Their Influence on Time to Diagnosis and Patient Outcome (QUICK-SEPSIS)

Run by Charite University, Berlin, Germany · NCT05383963 · Data updated 2026-11-12

This study is testing a new computer program that uses past medical records to see if it can help doctors diagnose sepsis and septic shock faster and more accurately for patients in the ICU.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorCharite University, Berlin, Germany
Academic / other
Locations1 site (Berlin)
StatusRecruiting
StartedJuly 15, 2022
Main results expectedSeptember 2026
Study endsDecember 2027
Registry record updatedDecember 1, 2025
Trial IDNCT05383963 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who have been in the ICU for more than 24 hours.

Probably not a fit

Patients who do not meet the age or ICU stay criteria may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study analyzes retrospective data from medical records to develop a machine learning algorithm aimed at enhancing the diagnosis of sepsis and septic shock. The study will evaluate how various parameters influence the time to diagnosis and patient outcomes. By focusing on data collected from ICU patients over a 14-year period, the research seeks to validate the predictive value of the algorithm and improve treatment processes. The study will also assess the economic implications of enhanced diagnostic accuracy.

Why it matters

Potential benefit: If successful, this study could lead to faster and more accurate diagnoses of sepsis, improving patient outcomes and potentially saving lives.

How similar studies have gone: Other studies utilizing machine learning for sepsis diagnosis have shown promise, indicating that this approach could be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age \>= 18 years
* ICU stay of \> 24 hours

Exclusion Criteria:

* none

Where it's running

  • Department of Anesthesiology and Operative Intensive Care Medicine CCM/CVK, Charité - Universitätsmedizin Berlin
    Berlin, Germany
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.