Using renal resistive index to predict acute kidney injury in sepsis patients
Renal Resistive Index by Renal Doppler Ultrasound as a Predictor of Acute Kidney Injury and Evaluation of Fluid Administration in Sepsis Patients: Cohort Study
This study is testing if measuring kidney blood flow can help predict kidney problems in patients with sepsis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 45 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, Elgharbia) |
| Trial ID | NCT06009445 on ClinicalTrials.gov |
What this trial studies
This study investigates the role of renal resistive index (RRI) in predicting the development of acute kidney injury (AKI) in patients with sepsis. It focuses on monitoring changes in RRI values over a period of 7 days from admission to assess their correlation with AKI development. The study aims to enhance the understanding of fluid administration strategies in sepsis management by evaluating RRI as a potential predictive tool.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 21 years old who meet the Sepsis 3 criteria but are not in septic shock.
Not a fit: Patients who are pregnant, have severe renal insufficiency, or other specific renal conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and management of acute kidney injury in sepsis patients.
How similar studies have performed: While the use of renal resistive index in this context is being explored, similar studies have shown promise in using biomarkers for predicting kidney injury, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age over 21 years * meet Sepsis 3 criteria (potential source of infection , host response and organ dysfunction) but not in septic shock. Exclusion Criteria: * patients during pregnancy. * patients with hepatorenal syndrome. * Poor abdominal echogenicity eg.(morbid obesity ,increase intra abdominal pressure ) * Severe acute or chronic renal insufficiency . * Dialysis dependency. * Renal transplantation. * Known renal artery stenosis. * Mono-kidney, kidney tumor, anatomic kidney abnormalities.
Where this trial is running
Tanta, Elgharbia
- Tanta University Hospitals — Tanta, Elgharbia, Egypt (Recruiting)
Study contacts
- Principal investigator: Safinaz A Aboelfetoh, MBBCh — Anesthesiology, Faculty of Medicine, Tanta University, Egypt.
- Study coordinator: Safinaz A Aboelfetoh, MBBCh
- Email: noralamar34@gmail.com
- Phone: 00201148855752
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.