Home › Trials › NCT06323018
Clinical trial Recruiting at 1 site Interventional Ages 65 to 90

Using remote ischemic preconditioning to protect organs during hip surgery

Official title: Effects of Remote Ischaemic Preconditioning in Cemented Total Hip Arthroplasty: Randomized Controlled Trial

Run by University of Tartu · NCT06323018 · Data updated 2026-11-12

This study is testing if a special technique called remote ischemic preconditioning can help protect the hearts, kidneys, and brains of older patients during hip surgery.

Quick facts

Study typeInterventional
Ages65 Years to 90 Years
SexAll
Enrollment200 (estimated)
SponsorUniversity of Tartu
Academic / other
Locations1 site (Tartu, Tartu)
StatusRecruiting
StartedMarch 20, 2024
Main results expectedMarch 2026
Study endsMarch 2027
Registry record updatedApril 4, 2024
Trial IDNCT06323018 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients over 65 years old who are scheduled for total cemented hip arthroplasty.

Probably not a fit

Patients with a history of peripheral artery disease or contraindications to RIPC may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of remote ischemic preconditioning (RIPC) on patients undergoing cemented hip arthroplasty, particularly focusing on its potential to protect multiple organs from complications associated with the procedure. Cemented hip arthroplasty is often performed on elderly patients with osteoarthritis and multiple comorbidities, who are at risk for bone cement implantation syndrome. The study aims to determine if RIPC can mitigate cardiovascular, renal, and neurological complications that may arise during and after surgery. Participants will be randomly assigned to receive either RIPC or a sham treatment to assess the protective effects of the intervention.

Why it matters

Potential benefit: If successful, this approach could significantly reduce postoperative complications and improve recovery outcomes for elderly patients undergoing hip surgery.

How similar studies have gone: Previous studies have shown that remote ischemic preconditioning can provide protective effects in non-cardiac surgeries, suggesting potential for success in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* age \>65 years
* undergoing total hip cemented hip arthroplasty

Exclusion Criteria:

* previously diagnosed peripheral artery disease on both upper limb
* RIPC is contraindicated

Where it's running

  • University of Tartu
    Tartu, Tartu, Estonia     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
Browse more
Osteoarthritis, Hip 26Cardiovascular Diseases 365Bone Cement Implantation Syndrome 2Kidney Diseases 52University of Tartu 9
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.