Using reminiscence to help older cancer survivors cope with existential suffering

The Effects of a Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors With Cognitive Impairment

Not applicable Interventional The University of Hong Kong · NCT05525299

This study tests if talking about their past can help older cancer survivors with mild cognitive impairment feel better and cope with difficult feelings about life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment116 (estimated)
Ages65 Years and up
SexAll
SponsorThe University of Hong Kong Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Hong Kong)
Trial IDNCT05525299 on ClinicalTrials.gov

What this trial studies

This intervention focuses on older cancer survivors aged 65 and above who experience mild cognitive impairment and existential suffering. The study implements a reminiscence-based life review intervention consisting of six chatting sessions aimed at providing psychological and spiritual support. By engaging participants in discussions about their past experiences, the intervention seeks to alleviate psychological distress and enhance social support. The effectiveness of this approach will be evaluated to determine its impact on coping with existential issues.

Who should consider this trial

Good fit: Ideal candidates for this study are cancer survivors aged 65 and older with mild cognitive impairment who have completed primary treatment for non-metastatic cancer.

Not a fit: Patients diagnosed with dementia or those who cannot adequately comprehend Cantonese or English will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the psychological well-being and quality of life for older cancer survivors facing existential suffering.

How similar studies have performed: While reminiscence therapy has been used in various contexts, this specific approach targeting older cancer survivors with cognitive impairment is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged ≥ 65 years
* Diagnosed with stage I-III non-metastatic cancer
* Completed primary treatment with curative intent (surgery, chemotherapy, and/or radiation therapy) 6 months to 5 years prior to baseline assessments with no recurrence or occurrence of additional cancers
* identified as mild cognitive impairment by the HK-MoCA 5-Min Protocol cognitive assessment (≤ 7th age and education corrected percentile cutoff score)

Exclusion Criteria:

* Inadequate written and verbal Cantonese and/or English comprehension for study activities
* Diagnosed with dementia

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Existential SufferingMeaning of LifeCognitive FunctionPsychological DistressSocial Support
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.