Using reflexology to prevent neuropathy from oxaliplatin in colorectal cancer patients
Official title: Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer
Run by University Hospital, Toulouse · NCT06251297 · Data updated 2026-11-12
This study is testing if reflexology can help colorectal cancer patients feel better and reduce nerve pain while they are receiving oxaliplatin chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Toulouse, CHU de Toulouse) |
| Status | Recruiting |
| Started | April 29, 2024 |
| Main results expected | May 1, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 10, 2025 |
| Trial ID | NCT06251297 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are starting oxaliplatin chemotherapy for colorectal cancer and can provide informed consent.
✕Probably not a fit
Patients with pre-existing neuropathy or contraindications to reflexology will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study aims to evaluate the feasibility of using reflexology as a complementary treatment for patients undergoing oxaliplatin chemotherapy for colorectal cancer. Participants will receive reflexology sessions with each cycle of chemotherapy, and their quality of life and neuropathy symptoms will be assessed throughout the treatment period. The study is designed to gather initial data on the effectiveness of reflexology in managing chemotherapy-induced side effects, particularly neuropathy.
Why it matters
Potential benefit: If successful, this approach could help reduce the incidence of neuropathy in colorectal cancer patients receiving oxaliplatin, improving their quality of life.
How similar studies have gone: While reflexology has been explored in various supportive care contexts, this specific application in oxaliplatin-induced neuropathy is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age\>18 years treated for colorectal cancer in Digestive Oncology service Rangueil hospital * Initiation of intravenous oxaliplatin chemotherapy at 85 mg/m² on a bimonthly schedule. * Ability to understand and answer a self-questionnaire. * Life expectancy egal or over 12 weeks * Signed informed consent form Exclusion Criteria: * Pre-existing motor and/or sensitive neuropathy. * Reflexology treatment within the last 6 months. * Contraindication to reflexology: venous thrombosis, trauma, wound or metastasis of the foot. * Patient covered by a legal protection scheme.
Where it's running
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CHU de Toulouse
Toulouse, CHU de Toulouse, France Recruiting
Study contacts
- Principal investigator: Nadim FARES, MD — University Hospital, Toulouse
- Study coordinator: Nadim FARES, MD
- Email: fares.n@chu-toulouse.fr
- Phone: 05 61 32 21 42
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.