Using Radialis PET imaging to assess amyloid plaque in the brain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the Radialis PET imager as an alternative to standard PET imaging for assessing amyloid plaque burden in patients with cognitive impairment, particularly Alzheimer's disease. Given the anticipated increase in demand for amyloid PET scans due to new therapies, this research aims to determine if the Radialis PET imager can provide comparable imaging results. Participants will undergo a standard brain PET scan along with an additional scan using the Radialis PET imager to compare the effectiveness of both imaging methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥18 years
2. Patients with cognitive impairment undergoing the standard of care brain 18F-Florbetaben PET imaging.
3. Patients who can remain still for an additional scan of approximately 30-45 minutes.

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   Exclusion Criteria:

1\. Inability to provide informed consent. 2. Contraindication for PET examination as per institutional safety guidelines, including but not limited to pregnancy or inability to remain still for PET examination.

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Where it's running

• University Health Network, Toronto
  Toronto, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Ur Metser
• Email: ur.metser@uhn.ca
• Phone: 416-946-4501

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.