Using pupil measurements to predict delirium in ICU patients
Constructing a Model of Pupillary Parameters in Predicting Delirium Among Critically Ill Patients in the Intensive Unit
This study is testing if measuring pupils can help doctors spot delirium early in patients in the ICU.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei City) |
| Trial ID | NCT06187792 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the relationship between pupil parameters and delirium in critically ill patients in intensive care units (ICUs). By utilizing Automated Infrared Pupillometry, the study will assess the accuracy and predictive capability of pupil measurements in identifying delirium, while also determining optimal cut-off points for these parameters. The research will involve collecting data from ICU patients and correlating it with assessments using the Intensive Care Delirium Screening Checklist (ICDSC). The findings are expected to enhance early detection and prevention strategies for delirium in ICU settings.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill patients aged 18 and above who are admitted to the intensive care unit.
Not a fit: Patients with acute brain injuries, certain brain-related diseases, or those who are expected to stay in the ICU for less than 72 hours may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and management of delirium in critically ill patients, potentially reducing long-term cognitive impairment and mortality.
How similar studies have performed: While studies have explored the relationship between pupil parameters and neurological disorders, this specific approach using Automated Infrared Pupillometry in ICU delirium is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients admitted to the intensive care unit from internal and surgical departments. * Ages 18 and above. Exclusion Criteria: * Acute brain injury (hemorrhagic, ischemic stroke). * Other brain-related diseases (brain tumor, brain infection, oculomotor nerve paralysis, etc.). * Ophthalmic diseases that prevent monitoring of pupil measurements. * Patients with pre-hospital cardiac arrest or in-hospital cardiac arrest. * Estimated stay in the intensive care unit not exceeding 72 hours. * Refusal to participate in this study.
Where this trial is running
Taipei City
- Ming-Chen Chiang — Taipei City, Taiwan (Recruiting)
Study contacts
- Study coordinator: Ming-Chen Chiang
- Email: jane.c0203@gmail.com
- Phone: (886) 02-23123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.