Using probiotics to prevent gallstones in patients after weight loss surgery
Probiotics for Gallstones in Post-bariatric Surgery Patients
This study is testing whether taking probiotics can help prevent gallstones in people who have had weight loss surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Sponsor | Shandong Linglong Yingcheng Hospital Research network |
| Locations | 1 site (Yantai, Shandong) |
| Trial ID | NCT06287931 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of probiotics in preventing gallstone formation in patients who have undergone bariatric surgery. It aims to address the increased risk of gallstones associated with rapid weight loss and changes in bile composition following surgery. Participants will be divided into groups receiving either probiotics or ursodeoxycholic acid to evaluate their impact on gallstone prevention and gastrointestinal quality of life. Regular follow-ups will be conducted to monitor outcomes and adherence to the treatment regimen.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 20 to 60 who are undergoing bariatric surgery for morbid obesity and are willing to participate in follow-up assessments.
Not a fit: Patients who already have gallstones prior to bariatric surgery or those unwilling to take probiotics or participate in follow-ups may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a non-invasive method to reduce the incidence of gallstones in post-bariatric surgery patients, improving their overall health and quality of life.
How similar studies have performed: While the use of ursodeoxycholic acid has been studied for gallstone prevention, the application of probiotics in this context is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients receiving bariatric surgery for morbid obesity * Patiets at ages between 20 to 60 y/o * Patients willing to follow up regulary after bariatric surgery Exclusion Criteria: * Patients having gallstones before bariatric surgery * Patients refusing taking probiotics or refusing regular follow up after bariatric surgery
Where this trial is running
Yantai, Shandong
- Shandong Linglong Yingcheng Hospital — Yantai, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Xuan Qiu, MD
- Email: qiuxuan100@163.com
- Phone: 8618354280081
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.