Using probiotics to improve ear health in children with cleft palate

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of probiotics on the upper respiratory tract microbiome in children with cleft palate who are at risk for otitis media. Specifically, it aims to determine if administering Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis BB-12 can alter the bacterial composition in the nasopharynx and reduce the frequency of ear discharge after ventilation tube placement. The study will involve children diagnosed with cleft palate and will monitor their ear health over time. The approach seeks to provide a non-invasive treatment option that could improve quality of life for affected children and their families.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* cleft palate \& lip (uni/bilateral) or cleft palate
* No syndromal disorders

Exclusion Criteria:

* syndromal disorder
* history of ventilation tube placement

Where it's running

• University Hospital Antwerp
  Edegem, Antwerp, Belgium Recruiting

Study contacts

• Study coordinator: An Boudewyns, Prof
• Email: An.Boudewyns@uza.be
• Phone: 003238214791

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.