Using priming with transcranial magnetic stimulation to treat obsessive-compulsive disorder
Priming in Repetitive Transcranial Magnetic Stimulation (TMSr) in the Adjuvant Treatment of Obsessive Compulsive Disorder (OCD)
This study is testing if a special type of brain stimulation can help people with obsessive-compulsive disorder feel better when combined with regular treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Federal University of Paraíba Academic / other |
| Locations | 1 site (João Pessoa, Paraiba) |
| Trial ID | NCT06049706 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of priming stimulation using repetitive transcranial magnetic stimulation (rTMS) in patients with obsessive-compulsive disorder (OCD). It is a randomized, double-blind, sham-controlled trial involving 50 participants who will be divided into two groups: one receiving active priming stimulation and the other receiving sham stimulation. The study aims to determine if the priming stimulation enhances the outcomes of rTMS treatment compared to standard rTMS alone. Participants will undergo neuropsychological assessments and complete various questionnaires to evaluate their symptoms and quality of life.
Who should consider this trial
Good fit: Ideal candidates are right-handed adults aged 18 to 60 diagnosed with OCD who meet specific symptom severity criteria.
Not a fit: Patients who are pregnant, have cognitive deficits, or are currently undergoing psychotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a more effective treatment option for patients suffering from obsessive-compulsive disorder.
How similar studies have performed: While the use of rTMS for OCD has been explored, the specific approach of combining it with priming stimulation is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being right-handed; * Age between 18 and 60; * Diagnose of OCD according to DSM-5; * Score in YBOCS between 16 and 23; * No change in dose prescription in the previous 3 months; * Signature of informed consent term. Exclusion Criteria: * Being pregnant; * Having cognitive deficit; * Diagnose of drug use disorder; * In current psychotherapy (or interrupted in less than 3 months); * Diagnose of severe Major Depression; * Risk of suicide; * Patients with metallic implants in the brain; * Epileptics.
Where this trial is running
João Pessoa, Paraiba
- Federal University of Paraíba,Department of Psychology — João Pessoa, Paraiba, Brazil (Recruiting)
Study contacts
- Principal investigator: Suellen Andrade — Federal University of Paraiba
- Study coordinator: Suellen Andrade
- Email: suellenandrade@gmail.com
- Phone: 986046032
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.