Using presepsin levels to guide antibiotic treatment in thoracic aorta surgery patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of presepsin, a biomarker, to predict and manage postoperative complications in patients undergoing thoracic aorta surgery. By monitoring presepsin levels, the study aims to identify patients at risk for infections and adjust antibiotic therapy accordingly, specifically administering ampicillin/sulbactam if necessary. The research builds on previous findings that link presepsin levels to postoperative outcomes, with the goal of improving patient care and reducing complications. The study will evaluate the effectiveness of this tailored approach in enhancing recovery and minimizing inflammatory issues post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Thoracic aorta aneurysm/dissection

Exclusion Criteria:

Blood sample hemolysis

Where it's running

• Petrovsky Research National Centre of Surgery (Petrovsky NRCS)
  Moscow, Moscow, Russia Recruiting

Study contacts

• Principal investigator: Boris Akselrod, Professor — Petrovsky NRCS
• Study coordinator: Artem Gubko, Ph.D.
• Email: gubko@artvig.ru
• Phone: +79684241490

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.