Using Povidone Iodine during Hip and Knee Surgery
Evaluation of the Systemic Effect of Intraoperative Diluted Povidone Iodine Irrigation Using Urine Iodine and Thyroid Function Tests in Patients Undergoing Knee-Hip Arthroplasty
This study is testing if using a special iodine solution during hip and knee surgeries helps prevent infections and how much of it the body absorbs compared to regular salt water.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ankara University Academic / other |
| Locations | 1 site (Ankara) |
| Trial ID | NCT05599841 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of povidone iodine (PI) solution as an antimicrobial agent during hip and knee arthroplasty procedures. It aims to assess whether iodine from the PI solution is absorbed by the body during these surgeries. The study compares the effects of PI solution to saline solution in patients undergoing primary arthroplasty for osteoarthritis. By understanding the absorption of iodine, the study seeks to ensure patient safety and optimize surgical outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients with hip or knee osteoarthritis who are scheduled for primary arthroplasty.
Not a fit: Patients with abnormal thyroid function tests or a history of thyroid-related diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance surgical safety and reduce infection rates in hip and knee arthroplasty patients.
How similar studies have performed: While the use of povidone iodine is common in surgical settings, this specific investigation into iodine absorption during arthroplasty is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients with hip/knee osteoarthritis who undergo primary arthroplasty Exclusion Criteria: * Patients with abnormal thyroid function tests in the preoperative period, a history of the previous thyroid-related disease.
Where this trial is running
Ankara
- Ankara University Faculty of Medicine — Ankara, Turkey (Recruiting)
Study contacts
- Principal investigator: Hakan Kocaoglu, MD — Ankara University
- Study coordinator: Hakan Kocaoglu, MD
- Email: kocaoglu@ankara.edu.tr
- Phone: 00903125082321
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.