Using platelet rich plasma to treat infertility in men
Platelet Rich Plasma Testis
NA · Stanford University · NCT05479474
This study is testing if using platelet-rich plasma injections can help men with infertility, specifically those who have had trouble retrieving sperm, improve their chances of successful sperm extraction and IVF.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | Stanford University (other) |
| Locations | 1 site (Stanford, California) |
| Trial ID | NCT05479474 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of intratesticular injections of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in men suffering from infertility, specifically those with nonobstructive azoospermia who have previously undergone a failed sperm retrieval. The approach aims to determine if PRP can enhance the outcomes of testicular sperm extraction (TESE) procedures. By focusing on a population with limited treatment options after negative sperm retrieval attempts, the study seeks to provide new insights into potential fertility treatments.
Who should consider this trial
Good fit: Ideal candidates for this study are men over the age of 18 diagnosed with nonobstructive azoospermia who have experienced at least one failed sperm retrieval attempt.
Not a fit: Patients who have not been diagnosed with nonobstructive azoospermia or those who have not undergone a failed sperm retrieval procedure may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve sperm retrieval rates and fertility outcomes for men with nonobstructive azoospermia.
How similar studies have performed: While the approach of using PRP for fertility treatments is relatively novel, prior series have suggested potential improvements in TESE outcomes, indicating a promising avenue for further investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men over the age of 18 diagnosed with NOA and at least one failed TESE, negative mapping or negative biopsy Exclusion Criteria: \-
Where this trial is running
Stanford, California
- Stanford Urology Clinic — Stanford, California, United States (RECRUITING)
Study contacts
- Study coordinator: Satvir Basran
- Email: sbasran@stanford.edu
- Phone: 650-723-0948
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Male Infertility, Nonobstructive Azoospermia, Azoospermia