Using PET/MRI to predict outcomes in endometrial cancer patients
Stratifying Endometrial Cancer Patients Using a PET/MRI Prognostic Model
IRCCS San Raffaele · NCT04212910
This study is testing if a special type of imaging called PET/MRI can help doctors figure out which endometrial cancer patients are at higher risk before their surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 101 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | IRCCS San Raffaele (other) |
| Locations | 1 site (Milan) |
| Trial ID | NCT04212910 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop a non-invasive prognostic model for endometrial cancer patients by utilizing simultaneous PET/MRI imaging. The research focuses on collecting and analyzing data from these imaging techniques to stratify patients into high-risk and low-risk groups before surgery. By combining the strengths of MRI in local staging and PET in detecting nodal involvement, the study seeks to enhance preoperative assessment and improve treatment planning for patients with endometrial cancer.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years with histopathologically confirmed primary endometrial cancer who are eligible for surgical intervention.
Not a fit: Patients who are under 18 years old, unsuitable for surgery, or unable to undergo the necessary imaging due to medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more personalized treatment strategies and improved outcomes for patients with endometrial cancer.
How similar studies have performed: While the combination of PET and MRI for prognostic modeling is a novel approach, similar studies have shown promise in enhancing cancer staging and treatment planning.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * histopathological confirmation of a primary endometrial cancer * age \> 18 years * no contraindication to surgery (comorbidity, contraindication or lack of consent) * no contraindication to preoperative imaging * visible tumor at imaging * signed inform consent. Exclusion Criteria: * patients unsuitable for surgical intervention (comorbidity, contraindication or lack of consent, poor performance status) * age \< 18 years, c) inability to complete the needed imaging examination (ie, severe claustrophobia) * any additional medical condition that may significantly interfere with study compliance * all the contraindication for MRI (ie, pacemaker).
Where this trial is running
Milan
- IRCCS Ospedale San Raffaele — Milan, Italy (RECRUITING)
Study contacts
- Study coordinator: Stephanie Steidler, PhD
- Email: steidler.stephanie@hsr.it
- Phone: +39022643
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Endometrium Cancer, endometrium, cancer, PET-MRI, stratification