Using PET/MRI to Monitor Brain Inflammation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate central nervous system (CNS) inflammation by utilizing PET/MRI imaging techniques. It focuses on conditions such as ischemic stroke, autoimmune encephalitis, and multiple sclerosis, where inflammation plays a critical role. The study will monitor the inflammatory response driven by microglial cells, which are essential for diagnosing and treating CNS diseases. Participants will undergo PET-MRI scans using a specific radiotracer to assess inflammation levels in the brain and spinal cord.

Why it matters

Who can join: the full rules

Inclusion Criteria:

-Clinical diagnosis of ischemic stroke, autoimmune ecephalitis, Neuromyelitis optica spectrum disorders, or multiple sclerosis, etc.al

Exclusion Criteria:

* Claustrophobia
* Metal Implants
* Pregancy
* Breast-feeding
* Renal insufficiency (GFR \< 60 mL/min/1.73m2)
* Allergy or other contraindication to gadolinium-based MR contrast agent

Where it's running

• Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
  Wuhan, Hubei, China Recruiting

Study contacts

• Principal investigator: Wei Wang, MD — Tongji Hospital
• Study coordinator: Luo-qi Zhou, MD
• Email: zhouluoqi@tjh.tjmu.edu.cn
• Phone: 86-27-83663337

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.